NUMB Protein (DYKDDDDK Tag)
Kurzübersicht für NUMB Protein (DYKDDDDK Tag) (ABIN2727805)
Target
Alle NUMB Proteine anzeigenProtein-Typ
Spezies
Quelle
Applikation
Reinheit
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Aufreinigungstag / Konjugat
- Dieses NUMB Protein ist gelabelt mit DYKDDDDK Tag.
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Produktmerkmale
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- Recombinant human NUMB (C-term flag tag) protein expressed in Sf9 cells.
- Produced with end-sequenced ORF clone
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Applikationshinweise
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Kommentare
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The tag is located at the C-terminal.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 50 μg/mL
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Buffer
- 50 mM Tris-HCl pH 8.0, 150 mM NaCl, 10 % glycerol. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 5 months from receipt of products under proper storage and handling conditions.
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Lagerung
- -80 °C
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Informationen zur Lagerung
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- NUMB (Numb Homolog (NUMB))
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Andere Bezeichnung
- Numb
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Hintergrund
- Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of neurogenesis. Also involved postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. May also mediate local repair of brain ventricular wall damage. [UniProtKB/Swiss-Prot Function]
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Molekulargewicht
- 66 kDa
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NCBI Accession
- NP_001005744
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Pathways
- Cell-Cell Junction Organization
Target
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