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NUMB Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

NUMB Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Produktnummer ABIN2727803
  • Target Alle NUMB Proteine anzeigen
    NUMB (Numb Homolog (NUMB))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    Transcript Variant 1
    Spezies
    • 5
    • 3
    • 1
    Human
    Quelle
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses NUMB Protein ist gelabelt mit Myc-DYKDDDDK Tag.
    Applikation
    Antibody Production (AbP), Standard (STD)
    Produktmerkmale
    • Recombinant human NUMB (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Reinheit
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product NUMB Protein
  • Applikationshinweise
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Kommentare

    The tag is located at the C-terminal.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    NUMB (Numb Homolog (NUMB))
    Andere Bezeichnung
    Numb (NUMB Produkte)
    Synonyme
    C14orf41 Protein, S171 Protein, c14_5527 Protein, Nb Protein, NUMB, endocytic adaptor protein Protein, numb homolog (Drosophila) Protein, NUMB Protein, Numb Protein, numb Protein
    Hintergrund
    Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of neurogenesis. Also involved postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. May also mediate local repair of brain ventricular wall damage. [UniProtKB/Swiss-Prot Function]
    Molekulargewicht
    70.6 kDa
    NCBI Accession
    NP_001005743
    Pathways
    Cell-Cell Junction Organization
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