MCM3 Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2725631

Produktdetails

Target: MCM3 (Minichromosome Maintenance Complex Component 3 (MCM3))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses MCM3 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human MCM3 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: MCM3 (Minichromosome Maintenance Complex Component 3 (MCM3))

Andere Bezeichnung: Mcm3 (MCM3 Produkte)

Synonyme: HCC5 Protein, P1-MCM3 Protein, P1.h Protein, RLFB Protein, AL033361 Protein, C80350 Protein, Mcmd Protein, P1 Protein, p1.m Protein, cb32 Protein, chunp6867 Protein, wu:fa26g03 Protein, CG4206 Protein, DmMCM3 Protein, DmMcm3 Protein, DmeMCM3 Protein, Dmel\\CG4206 Protein, MCM3 Protein, McM3 Protein, Mcp-PCR2 Protein, PCR2 Protein, dMCM3 Protein, xmcm3 Protein, minichromosome maintenance complex component 3 Protein, MCM3 minichromosome maintenance deficient 3 (S. cerevisiae) Protein, Minichromosome maintenance 3 Protein, minichromosome maintenance complex component 3 L homeolog Protein, MCM complex subunit Mcm3 Protein, MCM3 Protein, mcm3 Protein, Mcm3 Protein, mcm3.L Protein

Hintergrund: The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact directly with MCM5/CDC46. This protein also interacts with and is acetylated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression. Two transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 90.8 kDa

NCBI Accession: NP_002379

Pathways: DNA Reparatur, Mitotic G1-G1/S Phases, DNA Replication, Chromatin Binding, Synthesis of DNA