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MAX Protein (Transcript Variant 1) (His tag)

Dieses Recombinant MAX-Protein wird in Escherichia coli (E. coli) produziert.
Produktnummer ABIN2725572

Kurzübersicht für MAX Protein (Transcript Variant 1) (His tag) (ABIN2725572)

Target

Alle MAX Proteine anzeigen
MAX (MYC Associated Factor X (MAX))

Protein-Typ

Recombinant

Spezies

  • 12
  • 1
  • 1
  • 1
  • 1
Human

Quelle

  • 5
  • 4
  • 4
  • 1
  • 1
Escherichia coli (E. coli)

Applikation

Antibody Production (AbP), Standard (STD)

Reinheit

> 95 % as determined by SDS-PAGE and Coomassie blue staining
  • Proteineigenschaft

    Transcript Variant 1

    Aufreinigungstag / Konjugat

    Dieses MAX Protein ist gelabelt mit His tag.

    Produktmerkmale

    • Recombinant human MAX (transcript variant 1) protein expressed in E. coli.
    • Produced with end-sequenced ORF clone

    Endotoxin-Niveau

    < 0.1 EU per μg protein as determined by LAL test
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  • Applikationshinweise

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    Kommentare

    The tag is located at the C-terminal.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Buffer

    Lyophilized from a 0.2 μM filtered solution of 20 mM Tris-HCl, 50 mM Imidazole, 250 mM NaCl, pH 8.5. Stable for at least 6 months from date of receipt under proper storage and handling conditions.

    Lagerung

    -80 °C

    Informationen zur Lagerung

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target

    MAX (MYC Associated Factor X (MAX))

    Andere Bezeichnung

    Max

    Hintergrund

    The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants.

    Molekulargewicht

    18.3 kDa

    NCBI Accession

    NP_002373

    Pathways

    Mitotic G1-G1/S Phases
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