MAX Protein (Transcript Variant 1) (His tag)
Kurzübersicht für MAX Protein (Transcript Variant 1) (His tag) (ABIN2725572)
Target
Alle MAX Proteine anzeigenProtein-Typ
Spezies
Quelle
Applikation
Reinheit
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Proteineigenschaft
- Transcript Variant 1
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Aufreinigungstag / Konjugat
- Dieses MAX Protein ist gelabelt mit His tag.
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Produktmerkmale
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- Recombinant human MAX (transcript variant 1) protein expressed in E. coli.
- Produced with end-sequenced ORF clone
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Endotoxin-Niveau
- < 0.1 EU per μg protein as determined by LAL test
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Applikationshinweise
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Kommentare
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The tag is located at the C-terminal.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- Lyophilized from a 0.2 μM filtered solution of 20 mM Tris-HCl, 50 mM Imidazole, 250 mM NaCl, pH 8.5. Stable for at least 6 months from date of receipt under proper storage and handling conditions.
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Lagerung
- -80 °C
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Informationen zur Lagerung
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- MAX (MYC Associated Factor X (MAX))
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Andere Bezeichnung
- Max
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Hintergrund
- The protein encoded by this gene is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It is able to form homodimers and heterodimers with other family members, which include Mad, Mxi1 and Myc. Myc is an oncoprotein implicated in cell proliferation, differentiation and apoptosis. The homodimers and heterodimers compete for a common DNA target site (the E box) and rearrangement among these dimer forms provides a complex system of transcriptional regulation. Mutations of this gene have been reported to be associated with hereditary pheochromocytoma. A pseudogene of this gene is located on the long arm of chromosome 7. Alternative splicing results in multiple transcript variants.
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Molekulargewicht
- 18.3 kDa
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NCBI Accession
- NP_002373
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Pathways
- Mitotic G1-G1/S Phases
Target
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