MACC1 Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2725110

Produktdetails

Target: MACC1 (Metastasis Associated in Colon Cancer 1 (MACC1))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses MACC1 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human MACC1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: MACC1 (Metastasis Associated in Colon Cancer 1 (MACC1))

Andere Bezeichnung: Macc1 (MACC1 Produkte)

Synonyme: 7A5 Protein, SH3BP4L Protein, 4732474O15Rik Protein, Gm267 Protein, 7a5 Protein, RGD1309838 Protein, MACC1, MET transcriptional regulator Protein, metastasis associated in colon cancer 1 Protein, MACC1 Protein, Macc1 Protein

Hintergrund: MACC1 is a key regulator of the hepatocyte growth factor (HGF MIM 142409)-HGF receptor (HGFR, or MET MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis-free survival (Stein et al., 2009 [PubMed 19098908]).[supplied by OMIM, Mar 2009].

Molekulargewicht: 96.5 kDa

NCBI Accession: NP_877439