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MACC1 Produkte

(Metastasis Associated in Colon Cancer 1 (MACC1))
MACC1 is a key regulator of the hepatocyte growth factor (HGF\; MIM 142409)-HGF receptor (HGFR, or MET\; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis-free survival (Stein et al., 2009 [PubMed 19098908]).[supplied by OMIM, Mar 2009].

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Ausgewählte MACC1 Kategorien

MACC1 Antikörper

High quality antibodies with extensive validation data.

MACC1 ELISA Kits

Reliable ELISA kits for a wide range of species.

MACC1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene MACC1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human, Rat
Applikation WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validierungen
  • (6)
  • (5)
Kat. Nr. ABIN706526
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC, IF
Validierungen
  • (3)
Kat. Nr. ABIN7159558
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation IHC (p), IF
Validierungen
  • (2)
Kat. Nr. ABIN5650059
Menge 100 μL
Datenblatt Datenblatt

Empfohlene MACC1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (2)
  • (1)
Kat. Nr. ABIN6957784
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6975740
Menge 96 tests
Datenblatt Datenblatt

Empfohlene MACC1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
  • (1)
Kat. Nr. ABIN3093653
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7386299
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN3010685
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren MACC1 Produkten

Shi, Song, Wang, Zhang, Zheng: "MACC‑1 antibody target therapy suppresses growth and migration of non‑small cell lung cancer." in: Molecular medicine reports, Vol. 16, Issue 5, pp. 7329-7336, (2017) (PubMed).

Montorsi, Guizzetti, Alecci, Caporali, Martello, Atene, Parenti, Pizzini, Zanovello, Bortoluzzi, Ferrari, Grande, Zanocco-Marani: "Loss of zfp36 expression in colorectal cancer correlates to wnt/ ß-catenin activity and enhances epithelial-to-mesenchymal transition through upregulation of zeb1, sox9 and macc1." in: Oncotarget, Vol. 7, Issue 37, pp. 59144-59157, (2016) (PubMed).

Liu, Pan, Guo, Wu, Guo, Peng, Wu, Zuo: "A new mechanism of trastuzumab resistance in gastric cancer: MACC1 promotes the Warburg effect via activation of the PI3K/AKT signaling pathway." in: Journal of hematology & oncology, Vol. 9, Issue 1, pp. 76, (2016) (PubMed).

Sun, Li, Dai, Tan, Zhao, Li, Wang: "Silence of MACC1 expression by RNA interference inhibits proliferation, invasion and metastasis, and promotes apoptosis in U251 human malignant glioma cells." in: Molecular medicine reports, Vol. 12, Issue 3, pp. 3423-31, (2015) (PubMed).

Ge, Meng, Zhou, Zhang, Ding: "Positive MACC1 expression correlates with invasive behaviors and postoperative liver metastasis in colon cancer." in: International journal of clinical and experimental medicine, Vol. 8, Issue 1, pp. 1094-100, (2015) (PubMed).

Koelzer, Herrmann, Zlobec, Karamitopoulou, Lugli, Stein: "Heterogeneity analysis of Metastasis Associated in Colon Cancer 1 (MACC1) for survival prognosis of colorectal cancer patients: a retrospective cohort study." in: BMC cancer, Vol. 15, pp. 160, (2015) (PubMed).

Li, Zhang, Zhao, Shi, Yao, Zhang, Guo, Liu: "Overexpression of MACC1 and the association with hepatocyte growth factor/c-Met in epithelial ovarian cancer." in: Oncology letters, Vol. 9, Issue 5, pp. 1989-1996, (2015) (PubMed).

Kuo, Wu, Chang, Huang, Lin, Yan, Sheu, Lu, Chang, Lai, Wang: "Low SOX17 expression is a prognostic factor and drives transcriptional dysregulation and esophageal cancer progression." in: International journal of cancer, Vol. 135, Issue 3, pp. 563-73, (2014) (PubMed).

Hagemann, Fuchs, Monoranu, Herrmann, Smith, Hohmann, Grabiec, Kessler, Dehghani, Löhr, Ernestus, Vince, Stein: "Impact of MACC1 on human malignant glioma progression and patients' unfavorable prognosis." in: Neuro-oncology, Vol. 15, Issue 12, pp. 1696-709, (2013) (PubMed).

Guo, Yang, Yao, Zhang, Da, Duan: "Expression of MACC1 and c-Met in human gastric cancer and its clinical significance." in: Cancer cell international, Vol. 13, Issue 1, pp. 121, (2013) (PubMed).

Synonyme und alternative Namen zu MACC1

MACC1, MET transcriptional regulator (MACC1), metastasis associated in colon cancer 1 (Macc1), MACC1, MET transcriptional regulator (Macc1), 7A5, 7a5, 4732474O15Rik, Gm267, RGD1309838, SH3BP4L

Bezeichner auf Proteinebene für MACC1

  • SH3 domain-containing protein 7a5
  • metastasis-associated in colon cancer protein 1
  • putative binding protein 7a5
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