Lamin B1 Protein (LMNB1) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2724477

Produktdetails

Target: Lamin B1 (LMNB1)

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses Lamin B1 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human Lamin-B1 (LMNB1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Referenzen

Baghirova, Hughes, Poirier, Kondo, Schulz: "Nuclear matrix metalloproteinase-2 in the cardiomyocyte and the ischemic-reperfused heart." in: Journal of molecular and cellular cardiology, Vol. 94, pp. 153-61, (2016) (PubMed).

Antigendetails

Target: Lamin B1 (LMNB1)

Andere Bezeichnung: Lamin-b1 (Lmnb1) (LMNB1 Produkte)

Hintergrund: This gene encodes one of the two B-type lamin proteins and is a component of the nuclear lamina. A duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD). Alternative splicing results in multiple transcript variants.

Molekulargewicht: 66.2 kDa

NCBI Accession: NP_005564

Pathways: Apoptose, Caspase Kaskade in der Apoptose