IGF2 Protein (Transcript Variant 1)

Produktnummer ABIN2723526

Produktdetails

Target: IGF2 (Insulin-Like Growth Factor 2 (IGF2))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Proteineigenschaft: Transcript Variant 1

Spezies: Human

Quelle: Escherichia coli (E. coli)

Applikation: Functional Studies (Func), Antibody Production (AbP), Protein Interaction (PI), Standard (STD)

Spezifität: Optimal preservation of protein structure, post-translational modifications and functions.

Produktmerkmale:

• Recombinant human Insulin-like growth factor II / IGF2 (transcript variant 1) protein expressed in E. coli.
• Produced with end-sequenced ORF clone
• Tested for bioactivity.

Reinheit: > 95 % as determined by SDS-PAGE and Coomassie blue staining

Endotoxin-Niveau: Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).

Biological Activity Comment: ED50 was determined by a cell proliferation assay using FDC-P1 cells is less than or equal to 2.0 ng/ml, corresponding to a specific activity of > 5 x 10^5 units/mg.

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2

Handhabung: Resuspend the protein in the desired concentration in proper buffer

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: IGF2 (Insulin-Like Growth Factor 2 (IGF2))

Andere Bezeichnung: Insulin-Like Growth Factor Ii,igf2 (IGF2 Produkte)

Synonyme: C11orf43 Protein, IGF-II Protein, PP9974 Protein, LOC100136550 Protein, igf2 Protein, igf2b Protein, wu:fc26e03 Protein, zgc:91781 Protein, igf-2 Protein, insigf Protein, pp9974 Protein, AL033362 Protein, Igf-2 Protein, Igf-II Protein, M6pr Protein, Mpr Protein, Peg2 Protein, IGFII Protein, RNIGF2 Protein, IGF-II-B Protein, igf2-a Protein, igf2-b Protein, insulin like growth factor 2 Protein, insulin-like growth factor II Protein, insulin-like growth factor 2a Protein, insulin like growth factor 2 S homeolog Protein, insulin-like growth factor 2 Protein, insulin-like growth factor 2 (somatomedin A) Protein, insulin like growth factor 2 L homeolog Protein, IGF2 Protein, LOC100136550 Protein, igf2a Protein, igf2.S Protein, Igf2 Protein, igf2.L Protein

Hintergrund: This gene encodes a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumour, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. A read-through INS-IGF2 gene exists, whose 5' region overlaps the INS gene and the 3' region overlaps this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 7.5 kDa

NCBI Accession: NP_000603

Pathways: Hormone Activity, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Regulation of Carbohydrate Metabolic Process, Activated T Cell Proliferation