DTX2 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
Kurzübersicht für DTX2 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag) (ABIN2719806)
Target
Alle DTX2 Proteine anzeigenProtein-Typ
Spezies
Quelle
Applikation
Reinheit
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Proteineigenschaft
- Transcript Variant 2
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Aufreinigungstag / Konjugat
- Dieses DTX2 Protein ist gelabelt mit Myc-DYKDDDDK Tag.
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Produktmerkmale
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- Recombinant human DTX2 / RNF58 (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
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Applikationshinweise
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays -
Kommentare
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The tag is located at the C-terminal.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 50 μg/mL
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Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
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Lagerung
- -80 °C
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Informationen zur Lagerung
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- DTX2 (Deltex Homolog 2 (DTX2))
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Andere Bezeichnung
- Dtx2,rnf58
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Hintergrund
- Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Functions as a ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity. [UniProtKB/Swiss-Prot Function]
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Molekulargewicht
- 67.1 kDa
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NCBI Accession
- NP_001096064
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Pathways
- Notch Signalweg
Target
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