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BDNF Protein (Brain-Derived Neurotrophic Factor) (Transcript Variant 6)

BDNF Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, Func, PI, STD Active
Produktnummer ABIN2715217
$356.40
Zzgl. Versandkosten $45.00 und $20.00 Trockeneis
10 μg
Lieferung in 4 bis 8 Werktagen
  • Target Alle BDNF Proteine anzeigen
    BDNF (Brain-Derived Neurotrophic Factor (BDNF))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Proteineigenschaft
    Transcript Variant 6
    Spezies
    • 19
    • 7
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Quelle
    • 30
    • 17
    • 2
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Applikation
    Antibody Production (AbP), Functional Studies (Func), Protein Interaction (PI), Standard (STD)
    Spezifität
    Optimal preservation of protein structure, post-translational modifications and functions.
    Produktmerkmale
    • Recombinant human BDNF (transcript variant 6) protein expressed in E. coli.
    • Produced with end-sequenced ORF clone
    • Tested for bioactivity.
    Reinheit
    > 95 % as determined by SDS-PAGE and Coomassie blue staining
    Endotoxin-Niveau
    Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
    Biological Activity Comment
    Determined by its ability to stimulate the proliferation of rat C6 cells. The expected ED50 for this effect is 0.5-1.0ug/mL.
  • Applikationshinweise
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Protein-protein interaction
    In vitro biochemical assays and cell-based functional assays
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2
    Handhabung
    Resuspend the protein in the desired concentration in proper buffer
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    BDNF (Brain-Derived Neurotrophic Factor (BDNF))
    Andere Bezeichnung
    Bdnf (BDNF Produkte)
    Synonyme
    ANON2, BULN2, bdnf-A, BDNF, bdnf, brain derived neurotrophic factor, brain-derived neurotrophic factor, brain-derived neurotrophic factor L homeolog, brain-derived neurotrophic factor S homeolog, BDNF, Bdnf, bdnf, bdnf.L, bdnf.S
    Hintergrund
    This gene encodes a member of the nerve growth factor family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. Binding of this protein to its cognate receptor promotes neuronal survival in the adult brain. Expression of this gene is reduced in Alzheimer's, Parkinson's, and Huntington's disease patients. This gene may play a role in the regulation of the stress response and in the biology of mood disorders.
    Molekulargewicht
    27 kDa
    NCBI Accession
    NP_733930
    Pathways
    RTK Signalweg, Synaptic Membrane, Feeding Behaviour, Dicarboxylic Acid Transport, Regulation of long-term Neuronal Synaptic Plasticity
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