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BCL2L1 Protein (BCL2-Like 1) (Transcript Variant 2)

BCL2L1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant > 95 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Produktnummer ABIN2715193
$468.00
Zzgl. Versandkosten $45.00 und $20.00 Trockeneis
10 μg
Lieferung in 4 bis 8 Werktagen
  • Target Alle BCL2L1 Proteine anzeigen
    BCL2L1 (BCL2-Like 1 (BCL2L1))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    Transcript Variant 2
    Spezies
    • 8
    • 4
    • 2
    Human
    Quelle
    • 8
    • 3
    • 2
    • 1
    Escherichia coli (E. coli)
    Applikation
    Antibody Production (AbP), Standard (STD)
    Produktmerkmale
    • Recombinant human Bcl-2-like 1 (transcript variant 2) protein expressed in E. coli.
    • Produced with end-sequenced ORF clone
    Reinheit
    > 95 % as determined by SDS-PAGE and Coomassie blue staining
    Endotoxin-Niveau
    < 0.1 EU per μg protein as determined by LAL test
  • Applikationshinweise
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    50 μg/mL
    Buffer
    20 mM HEPES, 50 mM KCl, 20 % Glycerol, pH 7.5. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    BCL2L1 (BCL2-Like 1 (BCL2L1))
    Andere Bezeichnung
    Bcl-2-Like 1 (BCL2L1 Produkte)
    Synonyme
    BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS, Bcl(X)L, Bcl-XL, Bcl-Xs, Bcl2l, BclX, bcl-x, Bcl-xl, Bclx, bcl-X, Bcl-xL, BCL-XL, BCL2L1, bcl-XL, bcl-x(l), bcl-xl/s, bcl-xs, bcl2l, bclx, bclxl, xR11, bcl-xl, blp1, cb1021, zfBLP1, BCL2 like 1, BCL2-like 1, Bcl2-like 1, BCL2-like 1 L homeolog, bcl2-like 1, BCL2L1, Bcl2l1, bcl2l1, bcl2l1.L
    Hintergrund
    The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Alternative splicing results in multiple transcript variants encoding two different isoforms. The longer isoform acts as an apoptotic inhibitor and the shorter isoform acts as an apoptotic activator.
    Molekulargewicht
    24.8 kDa
    NCBI Accession
    NP_001182
    Pathways
    Apoptose, Negative Regulation of intrinsic apoptotic Signaling
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