ARNT2 Protein (Aryl Hydrocarbon Receptor Nuclear Translocator 2) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2714934

Produktdetails

Target: ARNT2 (Aryl Hydrocarbon Receptor Nuclear Translocator 2 (ARNT2))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses ARNT2 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human ARNT2 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: ARNT2 (Aryl Hydrocarbon Receptor Nuclear Translocator 2 (ARNT2))

Andere Bezeichnung: Arnt2 (ARNT2 Produkte)

Synonyme: bHLHe1, Hif-2b, mKIAA0307, Arnt, arnt2X, arnt2a, chunp6921, zfARNT2, zfARNT2a, zfARNT2b, zfARNT2c, arnt2, MGC53123, arnt.2, MGC68805, ARNT2, aryl hydrocarbon receptor nuclear translocator 2, aryl-hydrocarbon receptor nuclear translocator 2, aryl hydrocarbon receptor nuclear translocator 2 S homeolog, aryl hydrocarbon receptor nuclear translocator S homeolog, ARNT2, Arnt2, arnt2, arnt2.S, arnt.S, LOC100067423

Hintergrund: This gene encodes a member of the basic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of transcription factors. The encoded protein acts as a partner for several sensor proteins of the bHLH-PAS family, forming heterodimers with the sensor proteins that bind regulatory DNA sequences in genes responsive to developmental and environmental stimuli. Under hypoxic conditions, the encoded protein complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive elements in enhancers and promoters of oxygen-responsive genes. A highly similar protein in mouse forms functional complexes with both aryl hydrocarbon receptors and Single-minded proteins, suggesting additional roles for the encoded protein in the metabolism of xenobiotic compounds and the regulation of neurogenesis, respectively.

Molekulargewicht: 78.5 kDa

NCBI Accession: NP_055677