ARNT2 Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2714934

Produktdetails

Target: ARNT2 (Aryl Hydrocarbon Receptor Nuclear Translocator 2 (ARNT2))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses ARNT2 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human ARNT2 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: ARNT2 (Aryl Hydrocarbon Receptor Nuclear Translocator 2 (ARNT2))

Andere Bezeichnung: Arnt2 (ARNT2 Produkte)

Synonyme: bHLHe1 Protein, Hif-2b Protein, mKIAA0307 Protein, Arnt Protein, arnt2X Protein, arnt2a Protein, chunp6921 Protein, zfARNT2 Protein, zfARNT2a Protein, zfARNT2b Protein, zfARNT2c Protein, arnt2 Protein, MGC53123 Protein, arnt.2 Protein, MGC68805 Protein, ARNT2 Protein, aryl hydrocarbon receptor nuclear translocator 2 Protein, aryl-hydrocarbon receptor nuclear translocator 2 Protein, aryl hydrocarbon receptor nuclear translocator 2 S homeolog Protein, aryl hydrocarbon receptor nuclear translocator S homeolog Protein, ARNT2 Protein, Arnt2 Protein, arnt2 Protein, arnt2.S Protein, arnt.S Protein, LOC100067423 Protein

Hintergrund: This gene encodes a member of the basic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of transcription factors. The encoded protein acts as a partner for several sensor proteins of the bHLH-PAS family, forming heterodimers with the sensor proteins that bind regulatory DNA sequences in genes responsive to developmental and environmental stimuli. Under hypoxic conditions, the encoded protein complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive elements in enhancers and promoters of oxygen-responsive genes. A highly similar protein in mouse forms functional complexes with both aryl hydrocarbon receptors and Single-minded proteins, suggesting additional roles for the encoded protein in the metabolism of xenobiotic compounds and the regulation of neurogenesis, respectively.

Molekulargewicht: 78.5 kDa

NCBI Accession: NP_055677

Pathways: Warburg Effekt