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APOE Protein (Myc-DYKDDDDK Tag)

Dieses Recombinant APOE-Protein wird in HEK-293 Cells produziert. Es ist 1 Publikation verfügbar.
Produktnummer ABIN2714829

Kurzübersicht für APOE Protein (Myc-DYKDDDDK Tag) (ABIN2714829)

Target

Alle APOE Proteine anzeigen
APOE (Apolipoprotein E (APOE))

Protein-Typ

Recombinant

Spezies

  • 15
  • 8
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  • 2
  • 1
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Human

Quelle

  • 17
  • 15
  • 9
  • 3
  • 1
HEK-293 Cells

Applikation

Antibody Production (AbP), Standard (STD)

Reinheit

> 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Aufreinigungstag / Konjugat

    Dieses APOE Protein ist gelabelt mit Myc-DYKDDDDK Tag.

    Produktmerkmale

    • Recombinant human Apolipoprotein E / Apo E protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
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  • Applikationshinweise

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    Kommentare

    The tag is located at the C-terminal.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    50 μg/mL

    Buffer

    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

    Lagerung

    -80 °C

    Informationen zur Lagerung

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Pan, Zhou, Mahsut, Rohm, Berejnaia, Price, Chen, Castro-Perez, Lassman, McLaren, Conway, Jensen, Thomas, Reyes-Soffer, Ginsberg, Gutstein, Cleary, Previs, Roddy: "Static and turnover kinetic measurement of protein biomarkers involved in triglyceride metabolism including apoB48 and apoA5 by LC/MS/MS." in: Journal of lipid research, Vol. 55, Issue 6, pp. 1179-87, (2016) (PubMed).

  • Target

    APOE (Apolipoprotein E (APOE))

    Andere Bezeichnung

    Apolipoprotein E,apo E

    Hintergrund

    The protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants.

    Molekulargewicht

    34.2 kDa

    NCBI Accession

    NP_000032

    Pathways

    Regulation of Cell Size, Lipid Metabolism
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