APOC3 Protein (Myc-DYKDDDDK Tag)

Produktnummer ABIN2714826

Dieses Recombinant APOC3-Protein wird in HEK-293 Cells produziert. Es ist 1 Publikation verfügbar.

Kurzübersicht für APOC3 Protein (Myc-DYKDDDDK Tag) (ABIN2714826)

Target: APOC3 (Apolipoprotein C-III (APOC3))

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Applikation: Antibody Production (AbP), Standard (STD)

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Produktdetails

Aufreinigungstag / Konjugat: Dieses APOC3 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Produktmerkmale:

• Recombinant human Apolipoprotein C III / ApoC3 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Referenzen

Pan, Zhou, Mahsut, Rohm, Berejnaia, Price, Chen, Castro-Perez, Lassman, McLaren, Conway, Jensen, Thomas, Reyes-Soffer, Ginsberg, Gutstein, Cleary, Previs, Roddy: "Static and turnover kinetic measurement of protein biomarkers involved in triglyceride metabolism including apoB48 and apoA5 by LC/MS/MS." in: Journal of lipid research, Vol. 55, Issue 6, pp. 1179-87, (2016) (PubMed).

Antigendetails

Target: APOC3 (Apolipoprotein C-III (APOC3))

Andere Bezeichnung: Apolipoprotein C III (Apo Ciii)

Hintergrund: Apolipoprotein C-III is a very low density lipoprotein (VLDL) protein. APOC3 inhibits lipoprotein lipase and hepatic lipase it is thought to delay catabolism of triglyceride-rich particles. The APOA1, APOC3 and APOA4 genes are closely linked in both rat and human genomes. The A-I and A-IV genes are transcribed from the same strand, while the A-1 and C-III genes are convergently transcribed. An increase in apoC-III levels induces the development of hypertriglyceridemia.

Molekulargewicht: 8.7 kDa

NCBI Accession: NP_000031

Pathways: Carbohydrate Homeostasis, Lipid Metabolism