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ANAPC5 Protein (Anaphase Promoting Complex Subunit 5) (Transcript Variant 1) (Myc-DYKDDDDK Tag)

ANAPC5 Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Produktnummer ABIN2714782
$1,019.70
Zzgl. Versandkosten $45.00 und $20.00 Trockeneis
20 μg
Lieferung in 11 Werktagen
  • Target Alle ANAPC5 Proteine anzeigen
    ANAPC5 (Anaphase Promoting Complex Subunit 5 (ANAPC5))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    Transcript Variant 1
    Spezies
    • 3
    • 1
    • 1
    Human
    Quelle
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses ANAPC5 Protein ist gelabelt mit Myc-DYKDDDDK Tag.
    Applikation
    Antibody Production (AbP), Standard (STD)
    Produktmerkmale
    • Recombinant human APC5 / ANAPC5 (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Reinheit
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Applikationshinweise
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Kommentare

    The tag is located at the C-terminal.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    ANAPC5 (Anaphase Promoting Complex Subunit 5 (ANAPC5))
    Andere Bezeichnung
    Apc5,anapc5 (ANAPC5 Produkte)
    Synonyme
    APC5, DDBDRAFT_0206386, DDBDRAFT_0234269, DDB_0206386, DDB_0234269, zgc:55800, wu:fb75a09, ANAPC5, MGC89697, 2510006G12Rik, AA408751, AA536819, AA986414, Anpc5, F12K11.7, F12K11_7, anaphase promoting complex subunit 5, anaphase-promoting complex subunit 5, anaphase promoting complex subunit 5 L homeolog, anaphase-promoting complex subunit, anaphase-promoting complex subunit Apc5, ANAPC5, anapc5, LOC100093215, anapc5.L, Anapc5, AT1G06590, apc5
    Hintergrund
    This gene encodes a tetratricopeptide repeat-containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for the proper ubiquitination function of APC/C and for the interaction of APC/C with transcription coactivators. It also interacts with polyA binding protein and represses internal ribosome entry site-mediated translation. Multiple transcript variants encoding different isoforms have been found for this gene. These differences cause translation initiation at a downstream AUG and result in a shorter protein (isoform b), compared to isoform a.
    Molekulargewicht
    84.9 kDa
    NCBI Accession
    NP_057321
    Pathways
    M Phase
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