AP2M1 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2714769

Produktdetails

Target: AP2M1 (Adaptor-Related Protein Complex 2, mu 1 Subunit (AP2M1))

Protein-Typ: Recombinant

Proteineigenschaft: Transcript Variant 2

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses AP2M1 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human AP2 complex subunit mu-1 / AP2M1 (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: AP2M1 (Adaptor-Related Protein Complex 2, mu 1 Subunit (AP2M1))

Andere Bezeichnung: Ap2 Complex Subunit mu-1,ap2m1 (AP2M1 Produkte)

Synonyme: AP50 Protein, CLAPM1 Protein, mu2 Protein, Ap50 Protein, Clapm1 Protein, cb34 Protein, Ap2m1 Protein, dpy-23 Protein, sb:cb34 Protein, zgc:55711 Protein, zgc:85653 Protein, wu:fa97a10 Protein, ap2m1-a Protein, ap2m1 Protein, zgc:56643 Protein, AP2M1 Protein, adaptor related protein complex 2 mu 1 subunit Protein, adaptor-related protein complex 2, mu 1 subunit Protein, adaptor-related protein complex 2, mu 1 subunit, a Protein, adaptor related protein complex 2 mu 1 subunit L homeolog Protein, adaptor-related protein complex 2, mu 1 subunit, b Protein, AP-2 complex subunit mu-1 Protein, clathrin coat assembly protein AP50 Protein, clathrin coat assembly protein ap50 Protein, AP2M1 Protein, Ap2m1 Protein, ap2m1a Protein, ap2m1.L Protein, ap2m1b Protein, ap2m1 Protein, cgd8_950 Protein, PY06523 Protein, PVX_118455 Protein, PVX_123590 Protein, CpipJ_CPIJ003697 Protein

Hintergrund: This gene encodes a subunit of the heterotetrameric coat assembly protein complex 2 (AP2), which belongs to the adaptor complexes medium subunits family. The encoded protein is required for the activity of a vacuolar ATPase, which is responsible for proton pumping occurring in the acidification of endosomes and lysosomes. The encoded protein may also play an important role in regulating the intracellular trafficking and function of CTLA-4 protein. Three transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 49.2 kDa

NCBI Accession: NP_001020376

Pathways: EGFR Signaling Pathway, Neurotrophin Signalübertragung, EGFR Downregulation, SARS-CoV-2 Protein Interaktom