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TUBA1A Protein (Tubulin, alpha 1a) (Myc-DYKDDDDK Tag)

Tuba1a Spezies: Human Wirt: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Produktnummer ABIN2714588
$1,019.70
Zzgl. Versandkosten $45.00 und $20.00 Trockeneis
20 μg
Lieferung in 11 Werktagen
  • Target Alle TUBA1A (Tuba1a) Proteine anzeigen
    TUBA1A (Tuba1a) (Tubulin, alpha 1a (Tuba1a))
    Protein-Typ
    Recombinant
    Spezies
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Quelle
    • 8
    • 3
    • 2
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses TUBA1A Protein ist gelabelt mit Myc-DYKDDDDK Tag.
    Applikation
    Antibody Production (AbP), Standard (STD)
    Produktmerkmale
    • Recombinant human alpha Tubulin / TUBA1A / TUBA3 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Reinheit
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Applikationshinweise
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Kommentare

    The tag is located at the C-terminal.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Lagerung
    -80 °C
    Informationen zur Lagerung
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    TUBA1A (Tuba1a) (Tubulin, alpha 1a (Tuba1a))
    Andere Bezeichnung
    alpha Tubulin,tuba1a,tuba3 (Tuba1a Produkte)
    Synonyme
    Tuba1, B-ALPHA-1, LIS3, TUBA3, Tuba-1, TUBA3D, TUBA3E, wu:fb37a10, 1t, ALPHA 84C, Alpha-Tubulin84B, BEST:LD32507, CG1913, DM1alpha, DTA1, Dmel\CG1913, T, TBA1_DROME, Talpha1, Tub, Tub 84B, Tub1C, Tuba84B, Tubalpha1, a-tub84B, a1t, aTub84B, alpha-Tub, alpha-Tub84B, alpha-tub, alpha-tub84B, alpha-tubulin, alpha-tubulin 84B, alpha1, alpha1t, alpha1tub, alpha1tub84B, alpha84B, alphaT, alphaTUB, alphaTUB84B, alphaTub, alphaTub1, alphaTub84, alphat-1, alphatub, alphatub84B, anon-EST:Liang-1.59, anon-EST:Liang-2.30, chr3R:2914276..2914416, clone 1.59, clone 2.30, l(3)84Bd, l(3)g3, ms(3)nc33, nc33, tub, tubA84B, tubalpha1, tubulin, TUBA1A, Tuba1a, Tuba2, alphatub84, b-alpha-1, lis3, tuba1a, tuba1a-a, tuba1a-b, tuba3, tubulin, alpha 1A, tubulin alpha 1a, tubulin, alpha 1a, tubulin alpha-1B chain, tubulin alpha-1A chain, tubulin alpha-3 chain-like, alpha-Tubulin at 84B, tubulin alpha 1a L homeolog, Tuba1a, TUBA1A, LOC608147, LOC100392817, LOC425049, tuba1a, alphaTub84B, LOC100051840, LOC100340483, LOC100726777, tuba1a.L
    Hintergrund
    Microtubules of the eukaryotic cytoskeleton perform essential and diverse functions and are composed of a heterodimer of alpha and beta tubulins. The genes encoding these microtubule constituents belong to the tubulin superfamily, which is composed of six distinct families. Genes from the alpha, beta and gamma tubulin families are found in all eukaryotes. The alpha and beta tubulins represent the major components of microtubules, while gamma tubulin plays a critical role in the nucleation of microtubule assembly. There are multiple alpha and beta tubulin genes, which are highly conserved among species. This gene encodes alpha tubulin and is highly similar to the mouse and rat Tuba1 genes. Northern blotting studies have shown that the gene expression is predominantly found in morphologically differentiated neurologic cells. This gene is one of three alpha-tubulin genes in a cluster on chromosome 12q. Mutations in this gene cause lissencephaly type 3 (LIS3) - a neurological condition characterized by microcephaly, mental retardation, and early-onset epilepsy and caused by defective neuronal migration. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
    Molekulargewicht
    50 kDa
    NCBI Accession
    NP_006000
    Pathways
    Microtubule Dynamics, M Phase
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