CD3 Protein (CD3) (DYKDDDDK-His Tag)

Produktnummer ABIN2713618

Produktdetails

Target: CD3

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses CD3 Protein ist gelabelt mit DYKDDDDK-His Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human CD3 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 1 x PBS, pH 7.4, 10 % glycerol. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: CD3

Andere Bezeichnung: CD3 (CD3 Produkte)

Synonyme: CD3 Protein, AI504783 Protein, CD3epsilon Protein, T3e Protein, cd3-gamma Protein, cd3g Protein, cd3g-a Protein, cd3g/d Protein, cd3gd Protein, t3g Protein, CD3e molecule Protein, CD3d molecule Protein, CD3 antigen, epsilon polypeptide Protein, CD3g molecule S homeolog Protein, CD3E Protein, CD3D Protein, Cd3e Protein, cd3g.S Protein

Hintergrund: The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.

Molekulargewicht: 14 kDa

NCBI Accession: NP_000724

Pathways: T-Zell Rezeptor Signalweg, Ubiquitin Proteasome Pathway