Poliovirus Receptor Protein (PVR) (Transcript Variant 2)

Produktnummer ABIN2713446

Dieses Recombinant Poliovirus Receptor-Protein wird in HEK-293 Cells produziert.

Kurzübersicht für Poliovirus Receptor Protein (PVR) (Transcript Variant 2) (ABIN2713446)

Target: Poliovirus Receptor (PVR)

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Applikation: Standard (STD), Antibody Production (AbP)

Reinheit: > 95 % as determined by SDS-PAGE and Coomassie blue staining

Produktdetails

Proteineigenschaft: Transcript Variant 2

Produktmerkmale:

• Recombinant human CD155 / PVR (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Endotoxin-Niveau: < 0.1 EU per μg protein as determined by LAL test

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 20 mM Phosphate buffer, 150 mM NaCl, pH 7.4. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: Poliovirus Receptor (PVR)

Andere Bezeichnung: Cd155,pvr

Hintergrund: The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 36.1 kDa

NCBI Accession: NP_001129240

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Cancer Immune Checkpoints, SARS-CoV-2 Protein Interaktom