Caspase 3 Protein (CASP3) (Myc-DYKDDDDK Tag)

Produktnummer ABIN2713205

Produktdetails

Target: Caspase 3 (CASP3)

Protein-Typ: Recombinant

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses Caspase 3 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

Applikation: Antibody Production (AbP), Standard (STD)

Produktmerkmale:

• Recombinant human Caspase-3 (transcript variant beta) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Reinheit: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Anwendungsinformationen

Applikationshinweise: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Kommentare:

The tag is located at the C-terminal.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Lagerung: -80 °C

Informationen zur Lagerung: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Antigendetails

Target: Caspase 3 (CASP3)

Andere Bezeichnung: Caspase-3 (CASP3 Produkte)

Synonyme: CPP32 Protein, CPP32B Protein, SCA-1 Protein, A830040C14Rik Protein, AC-3 Protein, Apopain Protein, CC3 Protein, Caspase-3 Protein, Lice Protein, Yama Protein, mldy Protein, xcpp32 Protein, casp3 Protein, zgc:100890 Protein, CASP-3 Protein, caspase-3 Protein, caspase 3 Protein, caspase 3 S homeolog Protein, caspase 3, apoptosis-related cysteine peptidase a Protein, caspase 3, apoptosis-related cysteine peptidase Protein, CASP3 Protein, Casp3 Protein, casp3.S Protein, casp3a Protein

Hintergrund: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.

Molekulargewicht: 31.4 kDa

NCBI Accession: NP_116786

Pathways: Apoptose, Caspase Kaskade in der Apoptose, Sensory Perception of Sound, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation