Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

Caspase 3 Protein (CASP3) (Myc-DYKDDDDK Tag)

Recombinant Caspase 3-Protein exprimiert in HEK-293 Cells.
Produktnummer ABIN2713205

Kurzübersicht für Caspase 3 Protein (CASP3) (Myc-DYKDDDDK Tag) (ABIN2713205)

Target

Alle Caspase 3 (CASP3) Proteine anzeigen
Caspase 3 (CASP3)

Protein-Typ

Recombinant

Spezies

  • 10
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Human

Quelle

  • 16
  • 9
  • 1
  • 1
HEK-293 Cells

Applikation

Antibody Production (AbP), Standard (STD)

Reinheit

> 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Aufreinigungstag / Konjugat

    Dieses Caspase 3 Protein ist gelabelt mit Myc-DYKDDDDK Tag.

    Produktmerkmale

    • Recombinant human Caspase-3 (transcript variant beta) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
  • Möchten Sie weitere Optionen für dieses Protein ?

    !
    Entdecken Sie unsere vordefinierten maßgeschneiderten Proteine und Proteinservices!

    Ihr Projekt erfordert weitere Anpassungen? Kontaktieren Sie uns und entdecken Sie unsere maßgeschneiderten Proteinlösungen

  • Applikationshinweise

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    Kommentare

    The tag is located at the C-terminal.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Konzentration

    50 μg/mL

    Buffer

    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

    Lagerung

    -80 °C

    Informationen zur Lagerung

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target

    Caspase 3 (CASP3)

    Andere Bezeichnung

    Caspase-3

    Hintergrund

    This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein.

    Molekulargewicht

    31.4 kDa

    NCBI Accession

    NP_116786

    Pathways

    Apoptose, Caspase Kaskade in der Apoptose, Sensory Perception of Sound, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation
Sie sind hier:
Chat with us!