XBP1 Protein (AA 2-160) (His tag)
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- Target Alle XBP1 Proteine anzeigen
- XBP1 (X-Box Binding Protein 1 (XBP1))
- Protein-Typ
- Recombinant
- Proteineigenschaft
- AA 2-160
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Aufreinigungstag / Konjugat
- Dieses XBP1 Protein ist gelabelt mit His tag.
- Applikation
- Western Blotting (WB), ELISA, Mass Spectrometry (MS), Neutralization (Neut)
- Reinheit
- ~95 %
- Top Product
- Discover our top product XBP1 Protein
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X-Box Binding Protein 1 (XBP1) (AA 1-261) protein (GST tag)
XBP1 Spezies: Human Wirt: Wheat germ Recombinant WB, ELISA, AA, AP
X-Box Binding Protein 1 (XBP1) (AA 1-185) protein (His tag)Crystallography grade XBP1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
X-Box Binding Protein 1 (XBP1) (AA 1-261) protein (Strep Tag)Crystallography grade XBP1 Spezies: Human Wirt: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
X-Box Binding Protein 1 (XBP1) (AA 1-193) protein (rho-1D4 tag)Crystallography grade XBP1 Spezies: Human Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
X-Box Binding Protein 1 (XBP1) (AA 196-261) protein (rho-1D4 tag)Crystallography grade XBP1 Spezies: Human Wirt: Insektenzellen Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Applikationshinweise
- This recombinant protein can be used for WB, ELISA, MS and neutralization assays.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- 1X PBS containing 0.1 % SDS
- Handhabung
- Avoid freeze/thaw cycles. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
- Lagerung
- -80 °C
- Informationen zur Lagerung
- Store in working aliquots at -70 °C.
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- Target
- XBP1 (X-Box Binding Protein 1 (XBP1))
- Andere Bezeichnung
- XBP1 (XBP1 Produkte)
- Synonyme
- treb5 Protein, xXBP1 Protein, xbp2 Protein, XBP1P1 Protein, XBPP1 Protein, xbp1 Protein, TREB5 Protein, XBP-1 Protein, XBP2 Protein, D11Ertd39e Protein, TREB-5 Protein, HTF Protein, cb918 Protein, id:ibd1195 Protein, trebf Protein, wu:fb02h05 Protein, wu:fb63f10 Protein, xbp1a Protein, xbp1b Protein, X-box binding protein 1 Protein, X-box binding protein 1 L homeolog Protein, xbp1 Protein, XBP1 Protein, Xbp1 Protein, xbp1.L Protein
- Hintergrund
- X box binding protein 1 (XBP-1) is a key protein in the mammalian unfolded protein response (UPR) that protects the cell against the stress of malfolded proteins in the endoplasmic reticulum (ER) (1). Upon sensing unfolded proteins, an ER transmembrane endonuclease and kinase termed IRE1p is activated and excises an intron from XBP-1 mRNA. The spliced XBP-1 mRNA results in a 371 amino acid protein (XBP-1s) which is then translocated to the nucleus where it binds to the regulatory elements of downstream genes. Together with other UPR transcription factors such as ATF6, XBP-1 stimulates the production of ER stress proteins including the ER resident protein chaperones glucose regulated protein (GRP) 78 and GRP94 (3,4).
- Molekulargewicht
- 25 kDa (Calculated)
- Gen-ID
- 7494
- OMIM
- 18148382
- UniProt
- P17861
- Pathways
- ER-Nucleus Signaling, Unfolded Protein Response
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