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VEGF 165 (Active) Protein

Dieses Recombinant VEGF 165-Protein wird in Escherichia coli (E. coli) exprimiert.
Produktnummer ABIN2469210
345,13 €
Zzgl. Versandkosten 20,00 € und MwSt
Lieferung nach: Deutschland
Lieferung in 6 bis 9 Werktagen

Kurzübersicht für VEGF 165 (Active) Protein (ABIN2469210)

Target

VEGF 165

Protein-Typ

Recombinant

Biologische Aktivität

Active

Spezies

  • 32
  • 3
  • 1
Ratte

Quelle

  • 17
  • 9
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
Escherichia coli (E. coli)

Reinheit

< 98 % by SDS-PAGE gel and HPLC analyses.
  • Sequenz

    MAPTTEGEQK AHEVVKFMDV YQRSYCRPIE TLVDIFQEYP DEIEYIFKPS CVPLMRCAGC CNDEALECVP TSESNVTMQI MRIKPHQSQH IGEMSFLQHS RCECRPKKDR TKPEKHCEPC SERRKHLFVQ DPQTCKCSCK NTDSRCKARQ LELNERTCRC DKPRR

    Produktmerkmale

    Biological activity was determined by the dose - dependent stimulation of the proliferation of Human umbilical vein endothelial cells (HUVEC). The expected ED50 is 4.0 - 8.0 ng/mL.

    Endotoxin-Niveau

    Endotoxin level is less than 0.1 ng per μg (1 EU/μg).
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  • Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Handhabung

    As with any protein, exposing VEGF165 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted VEGF165 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.

    Haltbarkeit

    24 months
  • Target

    VEGF 165

    Andere Bezeichnung

    VEGF165

    Hintergrund

    VEGF is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothellial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. Substantial evidence implicates VEGF in the induction of tumor metastasis and intra-ocular neovascular syndromes. VEGF signals through the three receptors , fms-like tyrosine kinase(flt-1), KDR gene product (the murine homolog of KDR is the flk-1 gene product) and the flt4 gene product. Recombinant rat VEGF is a 38.5 kDa disulfide-linked homodimeric protein consisting of two 165 amino acid polypeptide chains.

    Gen-ID

    83785

    NCBI Accession

    NP_001103803

    OMIM

    160358793
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