Placenta Growth Factor 1 (PIGF-1) (Active) Protein

Produktnummer ABIN2468975

Dieses Recombinant Placenta Growth Factor 1-Protein wird in Escherichia coli (E. coli) produziert.

Kurzübersicht für Placenta Growth Factor 1 (PIGF-1) (Active) Protein (ABIN2468975)

Target: Placenta Growth Factor 1 (PIGF-1)

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: Escherichia coli (E. coli)

Reinheit: < 95 % by SDS-PAGE gel and HPLC analyses.

Produktdetails

Sequenz: MLPAVPPQQW ALSAGNGSSE VEVVPFQEVW GRSYCRALER LVDVVSEYPS EVEHMFSPSC VSLLRCTGCC GDENLHCVPV ETANVTMQLL KIRSGDRPSY VELTFSQHVR CECRPLREKM KPERCGDAVP RR

Produktmerkmale: Biological activity was determined by its ability to chemoattract human monocytes of using a concentration range of 1.0 - 10.0 ng/mL.

Endotoxin-Niveau: Endotoxin level is less than 0.1 ng per μg (1 EU/μg).

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Handhabung: As with any protein, exposing PlGF-1 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

Lagerung: -20 °C

Informationen zur Lagerung: The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted PlGF-1 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.

Haltbarkeit: 24 months

Antigendetails

Target: Placenta Growth Factor 1 (PIGF-1)

Hintergrund: PlGF-1 is an angiogenic factor that belongs to the cysteine-knot superfamily of growth factors. PlGF-1 is expressed in placental tissues, colon and mammary carcinomas. It signals through the VEGFR-1/FLT1 receptor and stimulates endothelial cell proliferation and migration. Recombinant human PlGF-1 is a 29.7 kDa disulfide-linked homodimeric protein of two 131 amino acid polypeptide chains.

Gen-ID: 5228

NCBI Accession: NP_001193941

OMIM: 333033785

UniProt: P49763