TNFSF14 Protein
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- Target Alle TNFSF14 Proteine anzeigen
- TNFSF14 (Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14))
- Protein-Typ
- Recombinant
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Spezies
- Maus
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Quelle
- Escherichia coli (E. coli)
- Sequenz
- MRLHQRLGDI VAHLPDGGKG SWEKLIQDQR SHQANPAAHL TGANASLIGI GGPLLWETRL GLAFLRGLTY HDGALVTMEP GYYYVYSKVQ LSGVGCPQGL ANGLPITHGL YKRTSRYPKE LELLVSRRSP CGRANSSRVW WDSSFLGGVV HLEAGEEVVV RVPGNRLVRP RDGTRSYFGA FMV
- Reinheit
- < 98 % by SDS-PAGE gel and HPLC analyses.
- Endotoxin-Niveau
- Endotoxin level is less than 0.1 ng per μg (1 EU/μg).
- Top Product
- Discover our top product TNFSF14 Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Handhabung
- As with any protein, exposing LIGHT recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted LIGHT is stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.
- Haltbarkeit
- 24 months
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- Target
- TNFSF14 (Tumor Necrosis Factor (Ligand) Superfamily, Member 14 (TNFSF14))
- Abstract
- TNFSF14 Produkte
- Hintergrund
- LIGHT belongs to the TNF family of ligands, and can signal through the herpes virus entry mediator type A receptor (HVEM, TNFRSF14), LTbetaR, or bind to a decoy receptor, DcR3. It is expressed in splenocytes, activated PBL, CD+8 tumor infiltrating lymphocytes, granulocytes, and monocytes. LIGHT has the ability to active NFkB, to co-stimulate the activation of lymphocytes and to induce apoptosis in certain human tumor cells. Recombinant murine LIGHT is a 20.1 kDa protein containing 183 amino acid residues.
- Gen-ID
- 50930
- NCBI Accession
- NP_062291
- OMIM
- 9507195
- UniProt
- Q9QYH9
- Pathways
- Cancer Immune Checkpoints
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