IL-7 Protein

Produktnummer ABIN2468713

Recombinant IL-7-Protein exprimiert in Escherichia coli (E. coli).

Kurzübersicht für IL-7 Protein (ABIN2468713)

Target: IL-7 (IL7) (Interleukin 7 (IL7))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Ratte

Quelle: Escherichia coli (E. coli)

Reinheit: < 98 % by SDS-PAGE gel and HPLC analyses.

Produktdetails

Sequenz: MDCHIKDKDG KAFGSVLMIS INQLDKMTGT DSDCPNNEPN FFKKHLCDDT KEAAFLNRAA RKLRQFLKMN ISEEFNDHLL RVSDGTQTLV NCTSKEEKTI KEQKKNDPCF LKRLLREIKT CWNKILKGSI

Produktmerkmale: The ED50 was determined by the dose - dependent stimulation of the proliferation of murine 2E8 cells is < 2.0 ng/mL, corresponding to a specific activity of > 5 x 10⁶ units/mg.

Endotoxin-Niveau: Endotoxin level is less than 0.1 ng per μg (1 EU/μg).

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Handhabung: As with any protein, exposing IL-7 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

Lagerung: -20 °C

Informationen zur Lagerung: The recombinant protein is stable for at least 2 years from date of receipt at -20 °C. Reconstituted IL-7 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20 °C.

Haltbarkeit: 24 months

Antigendetails

Target: IL-7 (IL7) (Interleukin 7 (IL7))

Andere Bezeichnung: IL-7

Hintergrund: IL-7 is a hematopoietic growth factor which affects primarily early B and T cells. Produced by thymic stromal cells, spleen cells and keratinocytes, IL-7 can also co-stimulate the proliferation of mature T cells in combination with other factors such as ConA and IL-2. Human and murine IL-7 is cross-species reactive. Recombinant rat IL-7 is a 15.0 kDa protein containing 130 amino acid residues.

Gen-ID: 25647

NCBI Accession: NP_037242

OMIM: 40254788

UniProt: P56478

Pathways: JAK-STAT Signalweg