TYRO3 Protein (AA 41-428) (Fc Tag)

Produktnummer ABIN2181883

Produktdetails

Target: TYRO3 (TYRO3 Protein Tyrosine Kinase (TYRO3))

Protein-Typ: Recombinant

Proteineigenschaft: AA 41-428

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses TYRO3 Protein ist gelabelt mit Fc Tag.

Sequenz: AA 41-428

Produktmerkmale: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 68.2 kDa. The protein migrates as 85-110 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Reinheit: >95 % as determined by SDS-PAGE.

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1.0 EU per μg by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Tris with Glycine, Arginine and NaCl,  pH 7.5

Handhabung: Please avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).

Antigendetails

Target: TYRO3 (TYRO3 Protein Tyrosine Kinase (TYRO3))

Andere Bezeichnung: TYRO3 (TYRO3 Produkte)

Synonyme: TYRO3 Protein, brt Protein, byk Protein, dtk Protein, rse Protein, sky Protein, tif Protein, Xksy Protein, MGC145734 Protein, DKFZp469I0432 Protein, LOC100231598 Protein, BYK Protein, Dtk Protein, RSE Protein, Sky Protein, Tif Protein, Brt Protein, REK Protein, ksy Protein, xksy Protein, AI323366 Protein, Etk-2 Protein, Rse Protein, TYRO3 protein tyrosine kinase Protein, TYRO3 protein tyrosine kinase L homeolog Protein, TYRO3 protein tyrosine kinase 3 Protein, TYRO3 Protein, tyro3 Protein, Tyro3 Protein, tyro3.L Protein

Hintergrund: Tyrosine-protein kinase receptor TYRO3 is also known as Tyrosine-protein kinase BYK, DTK, RSE, SKY, TIF, which belongs to the protein kinase superfamily, Tyr protein kinase family and AXL/UFO subfamily. TYRO3 regulates many physiological processes including cell survival, migration and differentiation. TYRO3 activates the AKT survival pathway, including nuclear translocation of NF-kappa-B and up-regulation of transcription of NF-kappa-B-regulated genes. TYRO3 interacts (via N-terminus) with extracellular ligands TULP1 and GAS6 By similarity and also interacts with PIK3R1, this interaction increases PI3-kinase activity.

Molekulargewicht: 68.2 kDa

Pathways: RTK Signalweg