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TYRO3 Protein Tyrosine Kinase (TYRO3) (AA 41-428) protein (Fc Tag)

TYRO3 Spezies: Human Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Produktnummer ABIN2181883
$330.00
Zzgl. Versandkosten $45.00
Lieferung in 2 bis 3 Werktagen
  • Target Alle TYRO3 Proteine anzeigen
    TYRO3
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 41-428
    Spezies
    • 15
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Quelle
    • 6
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses TYRO3 Protein ist gelabelt mit Fc Tag.
    Sequenz
    AA 41-428
    Produktmerkmale
    This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 68.2 kDa. The protein migrates as 85-110 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
    Reinheit
    >95 % as determined by SDS-PAGE.
    Sterilität
    0.22 μm filtered
    Endotoxin-Niveau
    Less than 1.0 EU per μg by the LAL method.
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    Tris with Glycine, Arginine and NaCl,  pH 7.5
    Handhabung
    Please avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
  • Target
    TYRO3
    Andere Bezeichnung
    TYRO3 (TYRO3 Produkte)
    Synonyme
    TYRO3, brt, byk, dtk, rse, sky, tif, Xksy, MGC145734, DKFZp469I0432, LOC100231598, BYK, Dtk, RSE, Sky, Tif, Brt, REK, ksy, xksy, AI323366, Etk-2, Rse, TYRO3 protein tyrosine kinase, TYRO3 protein tyrosine kinase L homeolog, TYRO3 protein tyrosine kinase 3, TYRO3, tyro3, Tyro3, tyro3.L
    Hintergrund
    Tyrosine-protein kinase receptor TYRO3 is also known as Tyrosine-protein kinase BYK, DTK, RSE, SKY, TIF, which belongs to the protein kinase superfamily, Tyr protein kinase family and AXL/UFO subfamily. TYRO3 regulates many physiological processes including cell survival, migration and differentiation. TYRO3 activates the AKT survival pathway, including nuclear translocation of NF-kappa-B and up-regulation of transcription of NF-kappa-B-regulated genes. TYRO3 interacts (via N-terminus) with extracellular ligands TULP1 and GAS6 By similarity and also interacts with PIK3R1, this interaction increases PI3-kinase activity.
    Molekulargewicht
    68.2 kDa
    Pathways
    RTK Signalweg
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