TNFRSF6B Protein (AA 30-300) (Fc Tag)

Produktnummer ABIN2181857

Produktdetails

Target: TNFRSF6B (Tumor Necrosis Factor Receptor Superfamily, Member 6b, Decoy (TNFRSF6B))

Protein-Typ: Recombinant

Proteineigenschaft: AA 30-300

Spezies: Human

Quelle: HEK-293 Cells

Aufreinigungstag / Konjugat: Dieses TNFRSF6B Protein ist gelabelt mit Fc Tag.

Sequenz: AA 30-300

Produktmerkmale: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 56.4 kDa. The protein migrates as 64 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Reinheit: >90 % as determined by SDS-PAGE.

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1.0 EU per μg by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: Tris with Glycine, Arginine and NaCl,  pH 7.5

Handhabung: Please avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).

Antigendetails

Target: TNFRSF6B (Tumor Necrosis Factor Receptor Superfamily, Member 6b, Decoy (TNFRSF6B))

Andere Bezeichnung: DcR3 (TNFRSF6B Produkte)

Synonyme: DCR3 Protein, DJ583P15.1.1 Protein, M68 Protein, M68E Protein, TR6 Protein, dcr3 Protein, m68 Protein, tr6 Protein, TNF receptor superfamily member 6b Protein, tumor necrosis factor receptor superfamily, member 11b Protein, regulator of telomere elongation helicase 1 Protein, TNF receptor superfamily member 6b L homeolog Protein, TNFRSF6B Protein, tnfrsf11b Protein, RTEL1 Protein, tnfrsf6b Protein, tnfrsf6b.L Protein

Hintergrund: Tumor necrosis factor receptor superfamily member 6B (TNFRSF6B) is also known as Decoy Receptor 3 (DcR3), Decoy receptor for Fas ligand and M68, which belongs to the tumor necrosis factor receptor superfamily. TNFRSF6 is a soluble protein which contains four TNFR-Cys repeats. Unlike most of the other members of TNFR superfamily, TNFRSF6 is a soluble protein which contains no transmembrane domain. TNFRSF6B acts as a decoy receptor that competes with death receptors for ligand binding. The protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death and T cell activation as well as to induce angiogenesis via neutralization of TL1A.

Molekulargewicht: 56.2 kDa