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Tumor Necrosis Factor Receptor Superfamily, Member 6b, Decoy (TNFRSF6B) (AA 30-300) protein (Fc Tag) Protein

TNFRSF6B Spezies: Human Wirt: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE.
Produktnummer ABIN2181857
$346.50
Zzgl. Versandkosten $45.00
Lieferung in 21 bis 31 Werktagen
  • Target Alle TNFRSF6B Proteine anzeigen
    TNFRSF6B
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 30-300
    Spezies
    Human
    Quelle
    • 2
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses TNFRSF6B Protein ist gelabelt mit Fc Tag.
    Sequenz
    AA 30-300
    Produktmerkmale
    This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 56.4 kDa. The protein migrates as 64 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
    Reinheit
    >90 % as determined by SDS-PAGE.
    Sterilität
    0.22 μm filtered
    Endotoxin-Niveau
    Less than 1.0 EU per μg by the LAL method.
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    Tris with Glycine, Arginine and NaCl,  pH 7.5
    Handhabung
    Please avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
  • Target
    TNFRSF6B
    Andere Bezeichnung
    DcR3 (TNFRSF6B Produkte)
    Synonyme
    DCR3, DJ583P15.1.1, M68, M68E, TR6, dcr3, m68, tr6, TNF receptor superfamily member 6b, tumor necrosis factor receptor superfamily, member 11b, regulator of telomere elongation helicase 1, TNF receptor superfamily member 6b L homeolog, TNFRSF6B, tnfrsf11b, RTEL1, tnfrsf6b, tnfrsf6b.L
    Hintergrund
    Tumor necrosis factor receptor superfamily member 6B (TNFRSF6B) is also known as Decoy Receptor 3 (DcR3), Decoy receptor for Fas ligand and M68, which belongs to the tumor necrosis factor receptor superfamily. TNFRSF6 is a soluble protein which contains four TNFR-Cys repeats. Unlike most of the other members of TNFR superfamily, TNFRSF6 is a soluble protein which contains no transmembrane domain. TNFRSF6B acts as a decoy receptor that competes with death receptors for ligand binding. The protein is postulated to play a regulatory role in suppressing FasL- and LIGHT-mediated cell death and T cell activation as well as to induce angiogenesis via neutralization of TL1A.
    Molekulargewicht
    56.2 kDa
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