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Mucin 1 (MUC1) (AA 33-167) protein (Fc Tag) Protein

MUC1 Spezies: Human Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Produktnummer ABIN2181522
$275.00
Zzgl. Versandkosten $45.00
Lieferung in 5 Werktagen
  • Target Alle MUC1 Proteine anzeigen
    MUC1
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 33-167
    Spezies
    • 24
    • 8
    • 3
    • 3
    • 2
    Human
    Quelle
    • 13
    • 11
    • 8
    • 2
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses MUC1 Protein ist gelabelt mit Fc Tag.
    Sequenz
    AA 33-167
    Produktmerkmale
    This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 51.3 kDa. The protein migrates as 45-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
    Reinheit
    >95 % as determined by SDS-PAGE.
    Sterilität
    0.22 μm filtered
    Endotoxin-Niveau
    Less than 1.0 EU per μg by the LAL method.
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    50 mM Tris, 100 mM Glycine, pH 7.5
    Handhabung
    Please avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C-8 °C), After reconstitution under sterile conditions for 1 month (4 °C-8 °C) or 3 months (-20 °C to -70 °C).
  • Target
    MUC1
    Andere Bezeichnung
    Mucin-1 (MUC1 Produkte)
    Synonyme
    CA 15-3, CD227, EMA, H23AG, KL-6, MAM6, MCKD1, MUC-1, MUC-1/SEC, MUC-1/X, MUC1/ZD, PEM, PEMT, PUM, Muc-1, mucin 1, cell surface associated, mucin 1, transmembrane, MUC1, Muc1
    Hintergrund
    Mucin-1 (MUC1) is also known as Tumor-associated epithelial membrane antigen (EMA), Polymorphic epithelial mucin (PEM), Peanut-reactive urinary mucin (PUM), PEMT, Krebs von den Lungen-6 (KL-6), CD antigen CD227, Episialin, H23AG. MUC1 is a glycoprotein with extensive O-linked glycosylation of its extracellular domain. Mucins line the apical surface of epithelial cells in the lungs, stomach, intestines, eyes and several other organs. Mucins protect the body from infection by pathogen binding to oligosaccharides in the extracellular domain, preventing the pathogen from reaching the cell surface. Except protective function by binding to pathogens, MUC1 also functions in a cell signaling capacity. Overexpression of MUC1 is often associated with colon, breast, ovarian, lung and pancreatic cancers.
    Molekulargewicht
    40.8 kDa
    Pathways
    Negative Regulation of intrinsic apoptotic Signaling
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