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Interleukin 2 Receptor, beta (IL2RB) (AA 27-239) (Active) protein (Fc Tag) Protein

IL2RB Spezies: Human Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Produktnummer ABIN2181388
$385.00
Zzgl. Versandkosten $45.00
Lieferung in 11 Werktagen
  • Target Alle IL2 Receptor beta (IL2RB) Proteine anzeigen
    IL2 Receptor beta (IL2RB)
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Proteineigenschaft
    AA 27-239
    Spezies
    • 12
    • 8
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Quelle
    • 8
    • 6
    • 6
    • 4
    • 2
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses IL2 Receptor beta Protein ist gelabelt mit Fc Tag.
    Sequenz
    AA 27-239
    Produktmerkmale
    This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 50.7 kDa. The protein migrates as 60-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
    Reinheit
    >95 % as determined by SDS-PAGE.
    Sterilität
    0.22 μm filtered
    Endotoxin-Niveau
    Less than 1.0 EU per μg by the LAL method.
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    50 mM Tris, 100 mM Glycine, pH 7.5
    Handhabung
    Please avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
  • Target
    IL2 Receptor beta (IL2RB)
    Andere Bezeichnung
    IL-2 R beta (IL2RB Produkte)
    Synonyme
    IL2RB, il-2rb, CD122, IL15RB, P70-75, IL2RBC, IL-15Rbeta, IL15Rbeta, Il-2/15Rbeta, Il-2Rbeta, p70, interleukin 2 receptor subunit beta, interleukin-2 receptor subunit beta, interleukin 2 receptor, beta, interleukin 2 receptor, beta chain, IL2RB, LOC510185, il2rb, Il2rb
    Hintergrund
    Interleukin-2 receptor subunit beta (IL2RB) is also known as CD122, which Belongs to the type I cytokine receptor family. Type 4 subfamily. IL2RB contains 1 fibronectin type-III domain. IL2RB / CD122 is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2.
    Molekulargewicht
    50.7 kDa
    NCBI Accession
    NP_000869
    Pathways
    JAK-STAT Signalweg, Growth Factor Binding
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