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Frizzled Family Receptor 4 (FZD4) (AA 37-180) protein (Fc Tag) Protein

FZD4 Spezies: Human Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Produktnummer ABIN2181126
$286.00
Zzgl. Versandkosten $45.00
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  • Target Alle FZD4 Proteine anzeigen
    FZD4
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 37-180
    Spezies
    • 8
    • 2
    Human
    Quelle
    • 4
    • 3
    • 1
    • 1
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses FZD4 Protein ist gelabelt mit Fc Tag.
    Sequenz
    AA 37-180
    Produktmerkmale
    This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 42.9 kDa. The protein migrates as 50-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
    Reinheit
    >95 % as determined by SDS-PAGE.
    Sterilität
    0.22 μm filtered
    Endotoxin-Niveau
    Less than 1.0 EU per μg by the LAL method.
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Handhabung
    Please avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
  • Target
    FZD4
    Andere Bezeichnung
    Frizzled-4 (FZD4 Produkte)
    Synonyme
    CG4626, DFz4, Dfz4, Dm Fz4, Dmel\\CG4626, Fz4, anon-WO0170980.10, anon-WO0170980.11, fz1, zg01, CD344, EVR1, FEVR, FZD4S, Fz-4, FzE4, GPCR, hFz4, frizzled4, fz4, FZ-4, frizzled 4, frizzled class receptor 4, frizzled-4, frizzled class receptor 4 S homeolog, fz4, fzd4, Tsp_10376, FZD4, Fzd4, fzd4.S
    Hintergrund
    Frizzled-4 (FZD4) is also known as FzE4, CD344, which belongs to the G-protein coupled receptor Fz/Smo family. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. FZD4 contains one FZ (frizzled) domain. FZD4 may be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. FZD4 interacts with MAGI3 and norrin (NDP).
    Molekulargewicht
    42.9 kDa
    Pathways
    WNT Signalweg, Hormone Transport, Sensory Perception of Sound
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