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Fibroblast Growth Factor Receptor 4 (FGFR4) (AA 22-369) protein (His tag) Protein

FGFR4 Spezies: Human Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE.
Produktnummer ABIN2181099
$385.00
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  • Target Alle FGFR4 Proteine anzeigen
    FGFR4
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 22-369
    Spezies
    • 19
    • 6
    • 4
    • 1
    • 1
    • 1
    Human
    Quelle
    • 13
    • 6
    • 4
    • 3
    • 3
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses FGFR4 Protein ist gelabelt mit His tag.
    Sequenz
    AA 22-369
    Produktmerkmale
    This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 40 kDa. The protein migrates as 60 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
    Reinheit
    >95 % as determined by SDS-PAGE.
    Sterilität
    0.22 μm filtered
    Endotoxin-Niveau
    Less than 1.0 EU per μg by the LAL method.
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Handhabung
    Please avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
  • Target
    FGFR4
    Andere Bezeichnung
    FGF R4 (FGFR4 Produkte)
    Synonyme
    FGFR4, XFGFR-4, XFGFR-4a, cd334, fgfr-4, jtk2, tkf, xfgfr4, CD334, JTK2, TKF, Fgfr-4, etID309818.21, wu:fc13h10, zgc:111935, fgfr-4c, fgfr4, fibroblast growth factor receptor 4, fibroblast growth factor receptor 4 S homeolog, FGFR4, fgfr4, Fgfr4, fgfr4.S
    Hintergrund
    Fibroblast growth factor receptor 4(FGFR4) is also known as CD334, JTK2, hydroxyaryl-protein kinase, TKF, protein-tyrosine kinase . The FGFR4 gene provides instructions for making a protein called fibroblast growth factor receptor 4. This protein is part of a family of fibroblast growth factor receptors that share similar structures and functions. These receptor proteins play a role in important processes such as cell division, regulating cell growth and maturation, formation of blood vessels, wound healing, and embryo development.The FGFR4 protein interacts with specific growth factors to conduct signals from the environment outside the cell to the nucleus. The nucleus responds to these signals by switching on or off appropriate genes that help the cell adjust to changes in the environment. In response, the cell might divide, move, or mature to take on specialized functions. Although specific functions of FGFR4 remain unclear, studies indicate that the gene is involved in muscle development and the maturation of bone cells in the skull. The FGFR4 gene may also play a role in the development and maintenance of specialized cells (called foveal cones) in the light-sensitive layer (the retina) at the back of the eye.
    Molekulargewicht
    39.3 kDa
    NCBI Accession
    NP_002002
    Pathways
    RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Carbohydrate Homeostasis, Growth Factor Binding
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