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Cartilage Oligomeric Matrix Protein (COMP) (AA 21-757) protein (His tag) Protein

COMP Spezies: Human Wirt: HEK-293 Cells Recombinant >88 % as determined by SDS-PAGE.
Produktnummer ABIN2180897
$275.00
Zzgl. Versandkosten $45.00
Lieferung in 2 bis 3 Werktagen
  • Target Alle COMP Proteine anzeigen
    COMP
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 21-757
    Spezies
    • 5
    • 4
    • 4
    Human
    Quelle
    • 7
    • 2
    • 2
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses COMP Protein ist gelabelt mit His tag.
    Sequenz
    AA 21-757
    Produktmerkmale
    This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 82 kDa. The protein migrates as 110-130 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
    Reinheit
    >88 % as determined by SDS-PAGE.
    Sterilität
    0.22 μm filtered
    Endotoxin-Niveau
    Less than 1.0 EU per μg by the LAL method.
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    50 mM Tris, 150 mM NaCl, pH 7.5
    Handhabung
    Please avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
  • Target
    COMP
    Andere Bezeichnung
    COMP (COMP Produkte)
    Synonyme
    COMP, EDM1, EPD1, MED, PSACH, THBS5, TSP5, cartilage oligomeric matrix protein, COMP, sce3551, CJA_1292, Comp
    Hintergrund
    Cartilage oligomeric matrix protein (COMP) is also known as Thrombospondin-5 (TSP5), EDM1, EPD1, MED, PSACH, THBS5, which belongs to the thrombospondin family. COMP / TSP5 contains 4 EGF-like domains, 1 TSP C-terminal (TSPC) domain, 8 TSP type-3 repeats. Abundantly expressed in the chondrocyte extracellular matrix, and is also found in bone, tendon, ligament and synovium and blood vessels. COMP may play a role in the structural integrity of cartilage via its interaction with other extracellular matrix proteins such as the collagens and fibronectin. COMP can mediate the interaction of chondrocytes with the cartilage extracellular matrix through interaction with cell surface integrin receptors. Thrombospondin-5 could play a role in the pathogenesis of osteoarthritis. COMP is a marker of cartilage turnover.
    Molekulargewicht
    81.9 kDa
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