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CD27 Molecule (CD27) (AA 21-192) (Active) protein (Fc Tag)

CD27 Spezies: Human Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Produktnummer ABIN2180735
$297.00
Zzgl. Versandkosten $45.00
Lieferung in 11 Werktagen
  • Target Alle CD27 Proteine anzeigen
    CD27
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Proteineigenschaft
    AA 21-192
    Spezies
    • 15
    • 6
    • 3
    • 1
    Human
    Quelle
    • 6
    • 5
    • 5
    • 4
    • 2
    • 1
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses CD27 Protein ist gelabelt mit Fc Tag.
    Sequenz
    AA 21-192
    Produktmerkmale
    This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 45.9 kDa. The protein migrates as 45-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
    Reinheit
    >95 % as determined by SDS-PAGE.
    Sterilität
    0.22 μm filtered
    Endotoxin-Niveau
    Less than 1.0 EU per μg by the LAL method.
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    50 mM Tris, 100 mM Glycine, pH 7.5
    Handhabung
    Please avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
  • Target
    CD27
    Andere Bezeichnung
    CD27 (CD27 Produkte)
    Synonyme
    TNFRSF7, S152, Tnfrsf7, Tp55, S152. LPFS2, T14, CD27 molecule, CD27 antigen, CD27, Cd27
    Hintergrund
    CD Antigen CD27 is also known as Tumor necrosis factor receptor superfamily member 7 (TNFRSF7), which belongs to TNF-receptor superfamily. CD27 / TNFRSF7 is found in most T-lymphocytes. CD27 / TNFRSF7 is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-κB and MAPK8/JNK. CD27 has been shown to interact with SIVA1, TRAF2 and TRAF3.
    Molekulargewicht
    45.9 kDa
    NCBI Accession
    NP_001233
    Pathways
    Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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