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Natural Killer Cell Receptor 2B4 (CD244) (AA 22-221) (Active) protein (Fc Tag) Protein

CD244 Spezies: Human Wirt: HEK-293 Cells Recombinant >95 % as determined by SDS-PAGE. Active
Produktnummer ABIN2180732
$275.00
Zzgl. Versandkosten $45.00
Lieferung in 2 bis 3 Werktagen
  • Target Alle 2B4 (CD244) Proteine anzeigen
    2B4 (CD244)
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Proteineigenschaft
    AA 22-221
    Spezies
    • 16
    • 6
    • 3
    Human
    Quelle
    • 7
    • 6
    • 4
    • 3
    • 3
    • 1
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses 2B4 Protein ist gelabelt mit Fc Tag.
    Sequenz
    AA 22-221
    Produktmerkmale
    This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 48.9 kDa. As a result of glycosylation, the protein migrates as 65-80 kDa under reducing (R) condition, and 130-160 kDa under non-reducing (NR) condition (SDS-PAGE).
    Reinheit
    >95 % as determined by SDS-PAGE.
    Sterilität
    0.22 μm filtered
    Endotoxin-Niveau
    Less than 1.0 EU per μg by the LAL method.
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH 7.5
    Handhabung
    Please avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
  • Target
    2B4 (CD244)
    Andere Bezeichnung
    2B4 (CD244 Produkte)
    Synonyme
    CD244, 2B4, NAIL, NKR2B4, Nmrk, SLAMF4, C9.1, F730046O15Rik, Ly90, CD244 molecule, CD244 natural killer cell receptor 2B4, CD244, Cd244
    Hintergrund
    Natural killer cell receptor 2B4 is also known as NK cell type I receptor protein 2B4 (NKR2B4 or h2B4), SLAM family member 4 (SLAMF4), Signaling lymphocytic activation molecule 4, CD antigen CD244. NKR2B4 / CD244 contains two Ig-like (immunoglobulin-like) domains. CD244 is expressed in spleen, PBL, followed by lung, liver, testis and small intestine. CD244 interacts with CD48. Following phosphorylation, CD244 is able to recruit PTPN11/SHP-2 and SH2D1A/SAP. SLAMF4 modulate other receptor-ligand interactions to enhance leukocyte activation. CD244/2B4 is the only heterophilic receptor of SLAM family.
    Molekulargewicht
    48.9 kDa
    NCBI Accession
    NP_057466
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