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2B4 Protein (Natural Killer Cell Receptor 2B4) (AA 22-221) (His tag,AVI tag,Biotin)

CD244 Spezies: Human Wirt: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE.
Produktnummer ABIN5674581
$1,675.38
Zzgl. Versandkosten $45.00
Lieferung in 5 Werktagen
  • Target Alle 2B4 (CD244) Proteine anzeigen
    2B4 (CD244) (Natural Killer Cell Receptor 2B4 (CD244))
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 22-221
    Spezies
    • 16
    • 6
    • 3
    Human
    Quelle
    • 8
    • 6
    • 4
    • 3
    • 2
    • 1
    • 1
    HEK-293 Cells
    Aufreinigungstag / Konjugat
    Dieses 2B4 Protein ist gelabelt mit His tag,AVI tag,Biotin.
    Marke
    PrecisionAvi
    Sequenz
    AA 22-221
    Spezifität
    Biotinylation of this product is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.
    Produktmerkmale
    This protein carries an Avi tag (Avitag™) at the C-terminus, followed by a polyhistidine tag. The protein has a calculated MW of 25.4 kDa. The protein migrates as 40-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
    Reinheit
    >90 % as determined by SDS-PAGE.
    Endotoxin-Niveau
    Less than 1.0 EU per μg by the LAL method.
  • Kommentare

    Ready-to-use AvitagTM biotinylated protein:
    The product is exclusively produced using the AvitagTM technology. Briefly, a unique 15 amino acid peptide, the Avi tag, is introduced into the recombinant protein during expression vector construction. The single lysine residue in the Avi tag is enzymatically biotinylated by the E. Coli biotin ligase BirA.

    This single-point enzymatic labeling technique brings many advantages for commonly used binding assays. The biotinylation happens on the lysine residue of Avi tag, and therefore does NOT interfere with the target protein's natural binding activities. In addition, when immobilized on an avidin-coated surface, the protein orientation is uniform because the position of the Avi tag in the protein is precisely controlled.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Handhabung
    Please avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
  • Target
    2B4 (CD244) (Natural Killer Cell Receptor 2B4 (CD244))
    Andere Bezeichnung
    2B4 (CD244 Produkte)
    Synonyme
    CD244, 2B4, NAIL, NKR2B4, Nmrk, SLAMF4, C9.1, F730046O15Rik, Ly90, CD244 molecule, CD244 natural killer cell receptor 2B4, CD244, Cd244
    Hintergrund
    Natural killer cell receptor 2B4 is also known as NK cell type I receptor protein 2B4 (NKR2B4 or h2B4), SLAM family member 4 (SLAMF4), Signaling lymphocytic activation molecule 4, CD antigen CD244. NKR2B4 / CD244 contains two Ig-like (immunoglobulin-like) domains. CD244 is expressed in spleen, PBL, followed by lung, liver, testis and small intestine. CD244 interacts with CD48. Following phosphorylation, CD244 is able to recruit PTPN11/SHP-2 and SH2D1A/SAP. SLAMF4 modulate other receptor-ligand interactions to enhance leukocyte activation. CD244/2B4 is the only heterophilic receptor of SLAM family.
    Molekulargewicht
    25.4 kDa
    NCBI Accession
    NP_057466
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