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BCL2-Like 1 (BCL2L1) (AA 2-212) protein (GST tag) Protein

BCL2L1 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant >92 % as determined by SDS-PAGE.
Produktnummer ABIN2180640
$275.00
Zzgl. Versandkosten $45.00
Lieferung in 2 bis 3 Werktagen
  • Target Alle BCL2L1 Proteine anzeigen
    BCL2L1
    Protein-Typ
    Recombinant
    Proteineigenschaft
    AA 2-212
    Spezies
    • 8
    • 4
    • 2
    Human
    Quelle
    • 8
    • 3
    • 2
    • 1
    Escherichia coli (E. coli)
    Aufreinigungstag / Konjugat
    Dieses BCL2L1 Protein ist gelabelt mit GST tag.
    Sequenz
    AA 2-212
    Produktmerkmale
    This protein carries a GST tag at the N-terminus. The protein has a calculated MW of 50.5 kDa. The protein migrates as 46 kDa under reducing (R) condition (SDS-PAGE).
    Reinheit
    >92 % as determined by SDS-PAGE.
    Sterilität
    0.22 μm filtered
    Endotoxin-Niveau
    Less than 1.0 EU per μg by the LAL method.
  • Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Buffer
    20 mM Tris, 100 mM NaCl, pH 7.5 with 10 mM GSH
    Handhabung
    Please avoid repeated freeze-thaw cycles.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    No activity loss was observed after storage at: In lyophilized state for 1 year (4 °C), After reconstitution under sterile conditions for 3 months (-70 °C).
  • Target
    BCL2L1
    Andere Bezeichnung
    Bcl-X (BCL2L1 Produkte)
    Synonyme
    BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS, Bcl(X)L, Bcl-XL, Bcl-Xs, Bcl2l, BclX, bcl-x, Bcl-xl, Bclx, bcl-X, Bcl-xL, BCL-XL, BCL2L1, bcl-XL, bcl-x(l), bcl-xl/s, bcl-xs, bcl2l, bclx, bclxl, xR11, bcl-xl, blp1, cb1021, zfBLP1, BCL2 like 1, BCL2-like 1, Bcl2-like 1, BCL2-like 1 L homeolog, bcl2-like 1, BCL2L1, Bcl2l1, bcl2l1, bcl2l1.L
    Hintergrund
    Bcl-2-like protein 1 (BCL2L1), is also known as Apoptosis regulator Bcl-X (Bcl-XL). BCL2L1 / Bcl-XL is a homodimer protein and belongs to the Bcl-2 family. BCL2L1 is expressed at high levels in cells that undergo a high rate of turnover, such as developing lymphocytes. BCL2L1 is a potent inhibitor of cell death. BCL2L1 Inhibits activation of caspases. BCL2L1 appears to regulate cell death by blocking the voltage-dependent anion channel (VDAC) by binding to it and preventing the release of the caspase activator, CYC1, from the mitochondrial membrane. BCL2L1 / Bcl-XL also acts as a regulator of G2 checkpoint and progression to cytokinesis during mitosis.
    Molekulargewicht
    50.6 kDa
    Pathways
    Apoptose, Negative Regulation of intrinsic apoptotic Signaling
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