Pleiotrophin Protein (PTN)
Kurzübersicht für Pleiotrophin Protein (PTN) (ABIN935709)
Target
Alle Pleiotrophin (PTN) Proteine anzeigenProtein-Typ
Spezies
Quelle
Reinheit
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Sequenz
- GKKEKPEKKV KKSDCGEWQW SVCVPTSGDC GLGTREGTRT GAECKQTMKT QRCKIPCNWK KQFGAECKYQ FQAWGECDLN TALKTRTGSL KRALHNAECQ KTVTISKPCG KLTKPKPQAE SKKKKKEGKK QEKMLD
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Produktmerkmale
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Purified recombinant Human Pleiotrophin protein
Expression System: E.coli -
Endotoxin-Niveau
- < 0.1 ng per μg (1 EU/μg).
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Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Reconstitute in water to a concentration of 0.1-1.0 mg/mL.
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Buffer
- Lyophilized from 5 mM Na3PO4, pH 7.4.
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Handhabung
- Avoid repeated freeze/thaw cycles.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store at 4 °C until reconstitution. Following reconstitution aliquot and freeze at -20 °C for long term storage.
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- Pleiotrophin (PTN)
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Andere Bezeichnung
- Pleiotrophin
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Hintergrund
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Pleiotrophin and Midkine are structurally related heparin-binding neurotrophic factors, whose expression is developmentally regulated. The expression pattern of these neurotrophic factors suggests function in neurogenesis, cell migration, secondary organogenetic induction, and mesoderm epithelial interaction. The expression of PTN increases during the process of brain embryogenesis and reaches maximum levels at time of birth. The physiological roles of PTN and Midkine are largely unknown, but these neurotrophins have been implicated in the pathogenesis of neuroblastomas.
Alternative Names: HBGF-8 protein, PTN protein, OSF-1 protein, HARP protein, Osteoblast-Specific Factor-1 protein, Heparin-binding growth factor-8protein, Heparin Affin Regulatory Protein protein -
Molekulargewicht
- 15.4 kDa
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Pathways
- RTK Signalweg
Target
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