FGF2 Protein
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- Target Alle FGF2 Proteine anzeigen
- FGF2 (Fibroblast Growth Factor 2 (Basic) (FGF2))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Sequenz
- AAGSITTLPA LPEDGGSGAF PPGHFKDPKR LYCKNGGFFL RIHPDGRVDG VREKSDPHIK LQLQAEERGV VSIKGVCANR YLAMKEDGRL LASKCVTDEC FFFERLESNN YNTYRSRKYT SWYVALKRTG QYKLGSKTGP GQKAILFLPM SAKS
- Produktmerkmale
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Purified recombinant Human FGF basic protein
Expression System: E.coli
Bioactivity: Assay #1: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors is ? 0.5 ng/mL, corresponding to a specific activity of ? 2 x 10^6 units/mg. Assay #2: The ED50 was determined by a cell proliferation assay using balb/c 3T3 cells is ? 0.1 ng/mL, corresponding to a specific activity of ? 1 x 10^7 units/mg. - Reinheit
- > 95 % pure
- Endotoxin-Niveau
- < 0.1 ng per μg (1 EU/μg).
- Top Product
- Discover our top product FGF2 Protein
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- Applikationshinweise
- Each Investigator should determine their own optimal working dilution for specific applications.
- Kommentare
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Biological activity: Assay #1: The ED50 as determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors is approx. 0.5 ng/mL, corresponding to a specific activity of approx. 2 x 10^6 units/mg. Assay #2: The ED50 was determined by a cell proliferation assay using balb/c 3T3 cells is approx. 0.1 ng/mL, corresponding to a specific activity of approx. 1 x 10^7 units/mg.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Reconstitute in 5 mM Tris, pH 7.6 to a concentration of 0.1 - 1.0 mg/mL.
- Buffer
- Lyophilized from 5 mM Tris, pH 7.6 with 155 mM NaCl.
- Handhabung
- Avoid repeated freeze/thaw cycles.
- Lagerung
- RT/-20 °C
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- Target
- FGF2 (Fibroblast Growth Factor 2 (Basic) (FGF2))
- Andere Bezeichnung
- FGF Basic (FGF2 Produkte)
- Synonyme
- BFGF Protein, FGF-2 Protein, FGFB Protein, HBGF-2 Protein, Fgf-2 Protein, Fgfb Protein, bFGF Protein, fibroblast growth factor 2 Protein, fibroblast growth factor 2 (basic) Protein, FGF2 Protein, Fgf2 Protein, fgf2 Protein
- Hintergrund
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FGF basic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF basic is a non-glycosylated heparin binding growth factor that is expressed in the brain, pituitary, kidney, retina, bone, testis, adrenal gland liver, monocytes, epithelial cells and endothelial cells. FGF basic signals through FGFR 1b, 1c, 2c, 3c and 4.
Alternative Names: FGF-2 protein, Prostatropin protein, Fibroblast Growth Factor-basic protein, HBGF-2 protein - Molekulargewicht
- 17.2 kDa
- Pathways
- RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, C21-Steroid Hormone Metabolic Process, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Protein targeting to Nucleus, S100 Proteine
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