CEA Protein

Produktnummer ABIN2128486

Dieses Native CEA-Protein wird in Human produziert. Es sind 3 Publikationen verfügbar.

Kurzübersicht für CEA Protein (ABIN2128486)

Target: CEA (Carcinoembryonic Antigen Gene Family (CEA))

Protein-Typ: Native

Spezies: Human

Quelle: Human

Reinheit: > 80 % pure

Produktdetails

Produktmerkmale: Purified native Human CEA protein
Protein Source: Purified human colon carcinoma

Aufreinigung: Immunoaffinity column

Anwendungsinformationen

Applikationshinweise: Each Investigator should determine their own optimal working dilution for specific applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Supplied as a liquid in 10 mM PBS, pH 7.5, with 0.1 % Sodium azide.

Vorsichtsmaßnahmen: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot and store at -20 °C.

Referenzen

Seifert, Kontermann: "GlycoTAIL and FlexiTAIL as Half-Life Extension Modules for Recombinant Antibody Fragments." in: Molecules (Basel, Switzerland), Vol. 27, Issue 10, (2022) (PubMed).

Martínez-Mancera, García-López, Hernández-López: "Pre-clinical validation study of a miniaturized electrochemical immunoassay based on square wave voltammetry for early detection of carcinoembryonic antigen in human serum." in: Clinica chimica acta; international journal of clinical chemistry, Vol. 444, pp. 199-205, (2015) (PubMed).

Lima, Jenkins, Guerrero, Triozzi, Shaw, Strong: "A DNA vaccine encoding genetic fusions of carcinoembryonic antigen (CEA) and granulocyte/macrophage colony-stimulating factor (GM-CSF)." in: Vaccine, Vol. 23, Issue 10, pp. 1273-83, (2005) (PubMed).

Antigendetails

Target: CEA (Carcinoembryonic Antigen Gene Family (CEA))

Andere Bezeichnung: CEA

Hintergrund: Carcinoembryonic antigen (CEA) is a glycoprotein involved in cell adhesion. It is normally produced during fetal development, but the production of CEA stops before birth. Therefore, it is not usually present in the blood of healthy adults, although levels are raised in heavy smokers. CEA is a glycosyl phosphatidyl inositol (GPI)-cell surface anchored glycoprotein whose specialized sialofucosylated glycoforms serve as functional colon carcinoma L-selectin and E-selectin ligands, which may be critical to the metastatic dissemination of colon carcinoma cells.
Description: Purified human colon carcinoma.
Alternative Names: Carcinoembryonic Antigen protein