CEA Protein (Biotin,His-Avi Tag)

Produktnummer ABIN7319778

Dieses Recombinant CEA-Protein wird in Human Cells produziert.

Kurzübersicht für CEA Protein (Biotin,His-Avi Tag) (ABIN7319778)

Target: CEA (Carcinoembryonic Antigen Gene Family (CEA))

Protein-Typ: Recombinant

Spezies: Human

Quelle: Human Cells

Reinheit: >95 % as determined by reducing SDS-PAGE.

Produktdetails

Aufreinigungstag / Konjugat: Dieses CEA Protein ist gelabelt mit Biotin,His-Avi Tag.

Verwendungszweck: Recombinant Human CEACAM5/CD66e/CEA (C-6His-Avi) Biotinylated

Sequenz: Lys35-Ala685

Produktmerkmale: Biotinylated Recombinant Human Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 is produced by our Mammalian expression system and the target gene encoding Lys35-Ala685 is expressed with a Avi, 6His tag at the C-terminus.

Endotoxin-Niveau: < 1.0 EU per μg as determined by the LAL method.

Anwendungsinformationen

Kommentare:

110-150 kDa

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Please refer to the printed manual for detailed information.

Buffer: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Antigendetails

Target: CEA (Carcinoembryonic Antigen Gene Family (CEA))

Andere Bezeichnung: CEA

Hintergrund:

Background: Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) belong to a group of mammalian immunoglobulin related glycoproteins. They play critical roles in cell-cell recognition. CEACAM5, also called CEA and CD66e, is characterized by having seven extracellular Ig domains and a glycosylphosphatidylinositol (GPI) anchor. CEACAM5 is expressed primarily by epithelial cells, and functions as a calcium-independent adhesion molecule through homophilic and heterophilic interactions with CEACAM1. Studies have shown that CEACAM5 is overexpressed in a majority of carcinomas, and its overexpression can protect tumor cells from apoptosis. It is commonly used as a cancer marker.

Synonym: Carcinoembryonic antigen-related cell adhesion molecule 5, Carcinoembryonic antigen, CEA, Meconium antigen 100, CD66e, CEACAM5

Molekulargewicht: 74.2 kDa

UniProt: P06731