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VEGF 165 (AA 27-191) (Active) Protein

Recombinant -Protein exprimiert in HEK-293T Cells.
Produktnummer ABIN2018445

Kurzübersicht für VEGF 165 (AA 27-191) (Active) Protein (ABIN2018445)

Target

VEGF 165

Protein-Typ

Recombinant

Biologische Aktivität

Active

Spezies

  • 19
  • 2
  • 1
Human

Quelle

  • 10
  • 7
  • 2
  • 1
  • 1
  • 1
HEK-293T Cells

Reinheit

> 95 % as analyzed by SDS-PAGE.
  • Proteineigenschaft

    AA 27-191

    Produktmerkmale

    ED50 <16 ng/mL, measured in a cell proliferation assay using HUVEC cells.

    Endotoxin-Niveau

    < 0.2 EU/μg, determined by LAL method.
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  • Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Rekonstitution

    Reconstituted in ddH2O or PBS at 100 μg/mL.

    Buffer

    Lyophilized after extensive dialysis against PBS.

    Lagerung

    -80 °C

    Informationen zur Lagerung

    Lyophilized recombinant Human Vascular Endothelial Growth Factor 165 (VEGF-165) remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, Human Vascular Endothelial Growth Factor 165 (VEGF-165) should be stable up to 1 week at 4°C or up to 2 months at -20°C.

    Haltbarkeit

    6 months
  • Target

    VEGF 165

    Andere Bezeichnung

    Vascular Endothelial Growth Factor 165 (VEGF165)

    Hintergrund

    Vascular Endothelial Growth Factor is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. Substantial evidence implicates VEGF in the induction of tumor metastasis and intra-ocular neovascular syndromes. VEGF signals through the three receptors, fms-like tyrosine kinase (flt-1), KDR gene product (the mouse homolog of KDR is the flk-1 gene product) and the flt4 gene product.
    Synonyms: Vascular Endothelial Growth Factor, VPF, Folliculostellate cell-derived growth factor, Glioma-derived endothelial cell mitogen

    Molekulargewicht

    20-26 kDa, observed by reducing SDS-PAGE.

    NCBI Accession

    NP_001165097
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