PDGFC Protein (AA 235-345)
Kurzübersicht für PDGFC Protein (AA 235-345) (ABIN2018318)
Target
Alle PDGFC Proteine anzeigenProtein-Typ
Biologische Aktivität
Spezies
Quelle
Reinheit
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Proteineigenschaft
- AA 235-345
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Produktmerkmale
- ED50 < 1 ng/mL, measured in a cell proliferation assay using 3T3 cells.
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Endotoxin-Niveau
- < 0.2 EU/μg, determined by LAL method.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL.
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Buffer
- Lyophilized after extensive dialysis against PBS.
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Lagerung
- -80 °C
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Informationen zur Lagerung
- Lyophilized recombinant Human Platelet-derived growth factor (PDGF) -CC remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Human Platelet-derived growth factor (PDGF) -CC should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
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Haltbarkeit
- 6 months
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- PDGFC (Platelet-Derived Growth Factor C (PDGFC))
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Substanzklasse
- Viral Protein
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Hintergrund
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Platelet-Derived Growth Factor (PDGF) is a potent mitogen for a wide range of cell types including fibroblasts, smooth muscle, connective tissue, bone and cartilage cells, and some blood cells. The PDGF is involved in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubule epithelial cell development. The PDGF family consists of proteins derived from four genes (PDGF -A, -B, -C, and -D) that form four disulfide-linked homodimers (PDGF-AA, -BB, -CC, and -DD) and one heterodimer (PDGF-AB).
Synonyms: PDGF -
Molekulargewicht
- 15-19 kDa, observed by reducing SDS-PAGE.
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NCBI Accession
- NP_057289
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Pathways
- RTK Signalweg, Platelet-derived growth Factor Receptor Signaling
Target
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