PDGFD Protein (AA 250-370)
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- Target Alle PDGFD Proteine anzeigen
- PDGFD (Platelet Derived Growth Factor D (PDGFD))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
- Proteineigenschaft
- AA 250-370
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Spezies
- Human
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Quelle
- CHO Cells
- Produktmerkmale
- ED50 < 5 μg/mL, measured in a cell proliferation assay using 3T3 cells.
- Reinheit
- > 95 % as analyzed by SDS-PAGE.
- Endotoxin-Niveau
- < 0.2 EU/μg, determined by LAL method.
- Top Product
- Discover our top product PDGFD Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL.
- Buffer
- Lyophilized after extensive dialysis against PBS.
- Lagerung
- -80 °C
- Informationen zur Lagerung
- Lyophilized recombinant human PDGF-DD remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, human PDGF-DDshould be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
- Haltbarkeit
- 6 months
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- Target
- PDGFD (Platelet Derived Growth Factor D (PDGFD))
- Abstract
- PDGFD Produkte
- Synonyme
- IEGF Protein, SCDGF-B Protein, SCDGFB Protein, Scdgfb Protein, rSCDGF-B Protein, PDGFD Protein, 1110003I09Rik Protein, platelet derived growth factor D Protein, platelet-derived growth factor, D polypeptide Protein, PDGFD Protein, Pdgfd Protein
- Hintergrund
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PDGF-DD, also known as platelet-derived growth factor D, IEGF and SCDGFB, is asecreted growth factor belonging to the PDGF/VEGFfamily. It is highly expressed in the heart, pancreas, adrenal glands and ovary. PDGF-DD forms functional homodimers that bind and induce PDGF Rbeta homodimers and PDGF R alpha/beta heterodimers that promote intracellular signaling. This plays an important role in the regulation of cell differentiation, migration and survival. It has also been reported that PDGF-DD can induce monocyte and macrophage recruitment, increase interstitial pressure and facilitate wound healing.
Synonyms: platelet-derived growth factor D, IEGF, SCDGFB - Molekulargewicht
- 19-21 kDa, observed by reducing SDS-PAGE.
- UniProt
- Q9GZP0
- Pathways
- RTK Signalweg, Platelet-derived growth Factor Receptor Signaling
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