PDGFD Protein (AA 250-370)

Produktnummer ABIN2018314

Dieses Recombinant PDGFD-Protein wird in CHO Cells exprimiert.

Kurzübersicht für PDGFD Protein (AA 250-370) (ABIN2018314)

Target: PDGFD (Platelet Derived Growth Factor D (PDGFD))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: CHO Cells

Reinheit: > 95 % as analyzed by SDS-PAGE.

Produktdetails

Proteineigenschaft: AA 250-370

Produktmerkmale: ED50 < 5 μg/mL, measured in a cell proliferation assay using 3T3 cells.

Endotoxin-Niveau: < 0.2 EU/μg, determined by LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstituted in ddH2O or PBS at 100 μg/mL.

Buffer: Lyophilized after extensive dialysis against PBS.

Lagerung: -80 °C

Informationen zur Lagerung: Lyophilized recombinant human PDGF-DD remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, human PDGF-DDshould be stable up to 1 week at 4 °C or up to 2 months at -20 °C.

Haltbarkeit: 6 months

Antigendetails

Target: PDGFD (Platelet Derived Growth Factor D (PDGFD))

Hintergrund: PDGF-DD, also known as platelet-derived growth factor D, IEGF and SCDGFB, is asecreted growth factor belonging to the PDGF/VEGFfamily. It is highly expressed in the heart, pancreas, adrenal glands and ovary. PDGF-DD forms functional homodimers that bind and induce PDGF Rbeta homodimers and PDGF R alpha/beta heterodimers that promote intracellular signaling. This plays an important role in the regulation of cell differentiation, migration and survival. It has also been reported that PDGF-DD can induce monocyte and macrophage recruitment, increase interstitial pressure and facilitate wound healing.
Synonyms: platelet-derived growth factor D, IEGF, SCDGFB

Molekulargewicht: 19-21 kDa, observed by reducing SDS-PAGE.

UniProt: Q9GZP0

Pathways: RTK Signalweg, Platelet-derived growth Factor Receptor Signaling