FGF7 Protein (AA 32-194)

Produktnummer ABIN2018177

Dieses Recombinant FGF7-Protein wird in CHO Cells produziert.

Kurzübersicht für FGF7 Protein (AA 32-194) (ABIN2018177)

Target: FGF7 (Fibroblast Growth Factor 7 (FGF7))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Human

Quelle: CHO Cells

Reinheit: > 95 % as analyzed by SDS-PAGE and HPLC.

Produktdetails

Proteineigenschaft: AA 32-194

Produktmerkmale: ED50 < 1 ng /mL, measured in a proliferation assay using 4MBr5 cells.

Endotoxin-Niveau: < 0.2 EU/μg, determined by LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstituted in ddH2O or PBS at 100 μg/mL.

Buffer: Lyophilized after extensive dialysis against PBS.

Lagerung: -80 °C

Informationen zur Lagerung: Lyophilized recombinant human Keratinocyte Growth Factor(rhKGF) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Human Keratinocyte Growth Factor should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.

Haltbarkeit: 6 months

Antigendetails

Target: FGF7 (Fibroblast Growth Factor 7 (FGF7))

Andere Bezeichnung: Keratinocyte Growth Factor (KGF)

Hintergrund: Keratinocyte Growth Factor (KGF), also known as FGF-7 and HBGF-7, is a mitogen factor belonging to the heparin-binding growth factor family. It is expressed mainly by epithelial cells. KGF binds to fibroblast growth factor receptor 2b (FGFR2b) to form a dimeric complex and initiate downstream signals. KGF plays an important role in embryonic development, cell proliferation and differentiation. It has also been reported to function in kidney and lung development, angiogenesis, wound healing and tumor invasion.
Synonyms: Keratinocyte Growth Factor, Fibroblast Growth Factor-7, HBGF-7

Molekulargewicht: 16-18 kDa, observed by reducing SDS-PAGE.

UniProt: P21781

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung