CXCL10 Protein (AA 22-98)
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- Target Alle CXCL10 Proteine anzeigen
- CXCL10 (Chemokine (C-X-C Motif) Ligand 10 (CXCL10))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
- Proteineigenschaft
- AA 22-98
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Spezies
- Human
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Quelle
- Escherichia coli (E. coli)
- Produktmerkmale
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ED50 < 0.2 μg/mL, measured by a cell proliferation assay of HUVEC cells in the presence of 2.5 ng/mL h-VEGF, corresponding to a specific activity of > 5.0x 10^3 IU/mg.
AA 22-98, expressed with an N-terminal Met. - Reinheit
- > 95 % by SDS-PAGE and HPLC analyses.
- Endotoxin-Niveau
- < 0.2 EU/μg, determined by LAL method.
- Top Product
- Discover our top product CXCL10 Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Reconstituted in ddH2O at 100 μg/mL.
- Buffer
- Lyophilized after extensive dialysis against 50 mM Tris, pH 8.0.
- Lagerung
- -80 °C
- Informationen zur Lagerung
- Lyophilized recombinant human IP-10/CXCL10 (rhIP-10) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rhIP-10 should be stable up to 2 weeks at 4 °C or up to 3 months at -20 °C.
- Haltbarkeit
- 6 months
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- Target
- CXCL10 (Chemokine (C-X-C Motif) Ligand 10 (CXCL10))
- Andere Bezeichnung
- IP-10/CXCL10 (CXCL10 Produkte)
- Synonyme
- CXCL10 Protein, C7 Protein, IFI10 Protein, INP10 Protein, IP-10 Protein, SCYB10 Protein, crg-2 Protein, gIP-10 Protein, mob-1 Protein, CRG-2 Protein, IP10 Protein, Ifi10 Protein, Scyb10 Protein, C-X-C motif chemokine ligand 10 Protein, C-X-C motif chemokine 10 Protein, chemokine (C-X-C motif) ligand 10 Protein, CXCL10 Protein, cxl10 Protein, Cxcl10 Protein
- Hintergrund
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IP-10/CXCL10 also known as CXCL10, is originally identified as an IFN-gamma-inducible gene in monocytes, fibroblasts and endothelial cells. It has since been shown that IP-10 mRNA is also induced by LPS, IL-1beta, TNF-alpha, IL-12 and viruses. Additional cell types that have been shown to express IP-10 include activated T-lymphocytes, splenocytes, keratinocytes, osteoblasts, astrocytes, and smooth muscle cells. IP-10 is also expressed in psoriatic and lepromatous lesions of skin. The mouse homologue of human IP-10, Crg-2, has been cloned and shown to share approximately 67 % amino acid sequence identity with human IP-10.Recombinant human IP-10/CXCL10 (rhIP-10) produced in E. coli is a single non-glycosylated polypeptide chain containing 78 amino acids. A fully biologically active molecule, rhIP-10 has a molecular mass of 8.6 kDa analyzed by reducing SDS-PAGE.
Synonyms: Small inducible cytokine B10, CXCL10, 10 kDa interferon-gamma-induced protein, Gamma-IP10, IP-10, chemokine (C-X-C motif) ligand 10, C7, IFI10, INP10, crg-2, mob-1, SCYB10, gIP-10 - Molekulargewicht
- 8.6 kDa, observed by reducing SDS-PAGE.
- UniProt
- P02778
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