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CXCL10 Protein (AA 22-98)

CXCL10 Spezies: Human Wirt: Escherichia coli (E. coli) Recombinant CMA Active
Produktnummer ABIN6952220
  • Target Alle CXCL10 Proteine anzeigen
    CXCL10 (Chemokine (C-X-C Motif) Ligand 10 (CXCL10))
    Protein-Typ
    Recombinant
    Biologische Aktivität
    Active
    Proteineigenschaft
    AA 22-98
    Spezies
    • 14
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Quelle
    • 23
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Applikation
    Cell Migration Assay (CMA)
    Sequenz
    VPLSRTVRCT CISISNQPVN PRSLEKLEII PASQFCPRVE IIATMKKKGE KRCLNPESKA IKNLLKAVSK ERSKRSP
    Produktmerkmale
    Recombinant Human CXCL10 (IP-10)
    Endotoxin-Niveau
    <0.01 EU per 1μg of the protein by the LAL method
    Biological Activity Comment
    EC50 = 6.3 nM determined by Migration Assay in cells expressing recombinant CXCR3
    Top Product
    Discover our top product CXCL10 Protein
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Spin tube prior to resuspending. Recommended at 100 μg/mL in sterile water
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    12 months from date of receipt, -20 to -70 °C as supplied.
    Suggest to use immediately after reconstitution
    1 month at -20 to -70 °C under sterile conditions after reconstitution.
    Haltbarkeit
    12 months
  • Target
    CXCL10 (Chemokine (C-X-C Motif) Ligand 10 (CXCL10))
    Andere Bezeichnung
    CXCL10 (IP-10) (CXCL10 Produkte)
    Synonyme
    CXCL10 Protein, C7 Protein, IFI10 Protein, INP10 Protein, IP-10 Protein, SCYB10 Protein, crg-2 Protein, gIP-10 Protein, mob-1 Protein, CRG-2 Protein, IP10 Protein, Ifi10 Protein, Scyb10 Protein, C-X-C motif chemokine ligand 10 Protein, C-X-C motif chemokine 10 Protein, chemokine (C-X-C motif) ligand 10 Protein, CXCL10 Protein, cxl10 Protein, Cxcl10 Protein
    Hintergrund
    CXCL10 (IP-10) was originally identified as an IFN-gamma-inducible gene in endothelial, fibroblasts and monocytes cells. IP-10 is considered a member of the CXC chemokine subfamily from its protein sequence which includes the four conserved cysteine residues present in CXC chemokines. IP-10 signals through the CXCR3 receptor to selectively attract Th1 lymphocytes and monocytes. It also has angiostatic and mitogenic properties on vascular smooth muscle cells. A diverse population of cell types rapidly increases transcription of mRNA encoding IP-10, which suggests that gamma-induced protein may be a key mediator of the IFNG/IFN-gamma response.
    Molekulargewicht
    8.646 kDa
    UniProt
    P02778
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