IL-5 Protein (AA 21-133)
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- Target Alle IL-5 (IL5) Proteine anzeigen
- IL-5 (IL5) (Interleukin 5 (IL5))
- Protein-Typ
- Recombinant
- Biologische Aktivität
- Active
- Proteineigenschaft
- AA 21-133
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Spezies
- Maus
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Quelle
- Escherichia coli (E. coli)
- Produktmerkmale
- ED50 < 2.0 ng/mL, measured by a cell proliferation assay using TF-1 Cells, corresponding to a specific activity of > 5.0x 10^5 units/mg.
- Reinheit
- > 95 % by SDS-PAGE and HPLC analyses.
- Endotoxin-Niveau
- < 0.2 EU/μg, determined by LAL method.
- Top Product
- Discover our top product IL5 Protein
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- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Reconstituted in ddH2O at 100 μg/mL.
- Buffer
- Lyophilized after extensive dialysis against PBS.
- Lagerung
- -80 °C
- Informationen zur Lagerung
- Lyophilized recombinant mouse Interleukin-5 (rmIL-5) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, rmIL-5 should be stable up to 2 weeks at 4 °C or up to 3 months at -20 °C.
- Haltbarkeit
- 6 months
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- Target
- IL-5 (IL5) (Interleukin 5 (IL5))
- Andere Bezeichnung
- Interleukin-5 (IL-5) (IL5 Produkte)
- Synonyme
- EDF Protein, IL-5 Protein, TRF Protein, Il-5 Protein, IL5 Protein, interleukin 5 Protein, IL5 Protein, Il5 Protein
- Hintergrund
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Interleukin-5 (rmIL-5),produced by mast cells, T cells and eosinophils, is responsible for the activities attributed to eosinophil differentiating factor, B cell growth factor II and T cell-replacing factor (TRF). It can increase production and mobilization of eosinophils and CD34+ progenitors from the bone marrow. IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. IL-5 also promotes differentiation of basophils and primes them for histamine and leukotriene release.Recombinant mouse Interleukin-5 (rmIL-5) produced in E.coli is a disulfide-linked homodimer containing two non-glycosylated polypeptide chains of 113 amino acids each. A fully biologically active molecule, rmIL-5 has a molecular mass of 26.2 kDa analyzed by non-reducing SDS-PAGE.
Synonyms: EDF,BCDFII,TRF - Molekulargewicht
- 26.2 kDa, observed by non-reducing SDS-PAGE.
- UniProt
- P04401
- Pathways
- JAK-STAT Signalweg, Positive Regulation of Peptide Hormone Secretion, Production of Molecular Mediator of Immune Response, Feeding Behaviour
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