IL-2 Protein (AA 21-153)
Kurzübersicht für IL-2 Protein (AA 21-153) (ABIN2018088)
Target
Alle IL-2 (IL2) Proteine anzeigenProtein-Typ
Biologische Aktivität
Spezies
Quelle
Reinheit
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Proteineigenschaft
- AA 21-153
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Produktmerkmale
- ED50 < 2 ng/mL, measured in a cell proliferation assay using CTLL-2 cells.
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Endotoxin-Niveau
- < 0.2 EU/μg, determined by LAL method.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Reconstituted in ddH2O or PBS at 100 μg/mL.
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Buffer
- Lyophilized after extensive dialysis against PBS..
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Lagerung
- -80 °C
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Informationen zur Lagerung
- Lyophilized recombinant Human Interleukin-2 (IL-2) remains stable up to 6 months at -80 °C from date of receipt. Upon reconstitution, Human Interleukin-2 (IL-2) should be stable up to 1 week at 4 °C or up to 2 months at -20 °C.
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Haltbarkeit
- 6 months
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- IL-2 (IL2) (Interleukin 2 (IL2))
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Andere Bezeichnung
- Interleukin-2 (IL-2)
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Hintergrund
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Interleukin-2 (IL-2) is a Oglycosylated, four alpha-helix bundle cytokine that has potent stimulatory activity for antigen-activated T cells. It is expressed by CD4+ and CD8+ T cells, gamma delta T cells, B cells, dendritic cells, and eosinophils. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions which are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine activated killer cells, monocytes, macrophages and oligodendrocytes.
Synonyms: T-cell growth factor (TCGF), Aldesleukin -
Molekulargewicht
- 15-16 kDa, observed by reducing SDS-PAGE.
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UniProt
- P60568
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Pathways
- JAK-STAT Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
Target
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